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Merck

CHRM3

cholinergic receptor, muscarinic 3

Synonyms:
EGBRS, HM3
Species:
Human CHRM3 (1131), Mouse Chrm3 (12671), Rat Chrm3 (24260), Domestic Rabbit CHRM3 (100355313), sheep CHRM3 (443189), domestic cat CHRM3 (101100919), cow CHRM3 (281685), Horse CHRM3 (100056633), dog CHRM3 (403827), domestic guinea pig Chrm3 (100379235)
UniProtKB ID:
P20309, Q0VAJ8, Q4QRI3, Q5VXY2, Q9HB60
Gene ID:
  • Human(1131) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq, Jul 2008]
  • Mouse(12671) cholinergic receptor, muscarinic 3, cardiac
  • Rat(24260) cholinergic receptor, muscarinic 3
  • Domestic Rabbit(100355313) cholinergic receptor, muscarinic 3
  • sheep(443189) cholinergic receptor, muscarinic 3
  • domestic cat(101100919) cholinergic receptor, muscarinic 3
  • cow(281685) cholinergic receptor, muscarinic 3
  • Horse(100056633) cholinergic receptor, muscarinic 3
  • dog(403827) cholinergic receptor, muscarinic 3
  • domestic guinea pig(100379235) cholinergic receptor, muscarinic 3, cardiac
  • chicken(396364) cholinergic receptor, muscarinic 3

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Small Molecule - Agonist

Product Number
Description
Species
A2661
Acetylcholine chloride, suitable for cell culture,
Species
human
A6625
Acetylcholine chloride, ≥99% (TLC),
Species
human
A9101
Acetylcholine chloride, pkg of 150 mg (per vial),
Species
human
PHR1943
Methacholine Chloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1008501
Acetylcholine chloride, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
H127
p-Fluorohexahydro-sila-difenidol hydrochloride, powder, ≥98% (HPLC),
Species
human
C3245000
Cyclopentolate hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP380
Cyclopentolate hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
1699005
Tropicamide, United States Pharmacopeia (USP) Reference Standard,
Species
human
BP1047
Tropicamide, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
AB9018
Anti-Muscarinic Acetylcholine Receptor m3 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
51330
Harmaline, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
Description
Species
A138
Aminobenztropine, solid,
Species
human

esiRNA

Product Number
Description
Species
EHU027151
MISSION® esiRNA, targeting human CHRM3,
Species
human