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Supelco

Discovery® C18 (5 µm) HPLC Columns

L × I.D. 2 cm × 4 mm HPLC guard Column Kit with 1 Cartridge holder + 1 Guard Cartridge

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About This Item

UNSPSC Code:
41115700

product name

Discovery® C18 Supelguard Guard Cartridge, Kit, 5 μm particle size, L × I.D. 2 cm × 4 mm

Agency

suitable for USP L1

Quality Level

packaging

pkg of 1 kit

technique(s)

HPLC: suitable

L × I.D.

2 cm × 4 mm

matrix active group

C18 (octadecyl) bonding phase

particle size

5 μm

pore size

180 Å

application(s)

food and beverages

compatibility

use to protect Discovery C18

separation technique

reversed phase

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General description

Discovery® C18 Supelguard Guard Cartridges [Kit, 5 μm particle size, L × I.D. 2 cm × 4 mm] contain a Discovery® packing, in a 2 cm stainless steel body, enclosed by polyether ether ketone (PEEK) encapsulated stainless steel frits (2 μm porosity). A Supelguard kit (one cartridge, a stand-alone holder, tubing, and 2 nuts and ferrules) enables one to use the cartridge with any analytical column. A direct-connect guard cartridge holder can directly connect a Supelguard cartridge to a Supelco analytical column. 3.0 mm cartridges are available in packs of two only-purchase a stand-alone or modular holder separately. Low volume 3.0 mm ID cartridges are a good choice for protecting an analytical column containing 3 μm particles.

Footnote

Kit includes one cartridge, a stand-alone holder, a piece of tubing, 2 nuts and ferrules.

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Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Yuan-Qing Xia et al.
Rapid communications in mass spectrometry : RCM, 20(12), 1831-1837 (2006-05-18)
A major challenge in selecting an appropriate stationary phase for diastereomeric separation is that it is difficult to predict which of the commercially available stationary phases could achieve the required liquid chromatographic (LC) separation. This work describes the selection and
Ramisetti Nageswara Rao et al.
Journal of separation science, 32(9), 1312-1322 (2009-04-29)
Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions indispensable for identification of the structures were
R Nageswara Rao et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 873(1), 119-123 (2008-08-30)
A highly sensitive and specific liquid chromatography/tandem mass spectrometric (LC-MS/MS) method for investigating the pharmacokinetics of adrafinil in rats was developed. Rat serum pretreated by solid-phase extraction (SPE) was analyzed by LC-MS/MS with an electrospray ionization (ESI) interface. The mobile
Satoru Sonoke et al.
Cancer research, 68(21), 8843-8851 (2008-11-01)
The pharmacokinetics and antitumor activity of pegylated small interfering RNA (siRNA)/cationic liposome complexes were studied after systemic administration to mice. We designed pegylated-lipid carriers for achieving increased plasma concentrations of RNA and hence improved accumulation of RNA in tumors by

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