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biological source
Canavalia ensiformis
Quality Level
form
solid
mol wt
hexamer 545 kDa
trimer ~272 kDa
contains
~20% dithiothreitol
suitability
suitable for marker for electrophoresis (non-denaturing PAGE)
storage temp.
−20°C
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General description
Subunit molecular weight: ~90,770
Composed of six subunits with total molecular weight: ~544,620
Composed of six subunits with total molecular weight: ~544,620
Urease is a multi-subunit nickel-dependent metalloenzyme. It is found abundantly in fungi, yeast, plants, and bacteria. It belongs to the superfamily of amidohydrolases and phosphotriesterases. Urease is also found in leguminous seeds.
Application
Urease from Canavalia ensiformis (Jack bean) has been used:
- as a component of the molecular mass standard in electrophoresis
- as a component of the standard in size-exclusion chromatography
- as a reference in native-polyacrylamide gel electrophoresis (PAGE)
Biochem/physiol Actions
Urease is an essential enzyme of the nitrogen cycle. It plays a role in degrading urea into ammonia and carbamate. Urease provides a source of nitrogen for growth to various organisms. It also plays a major role in seed germination and seed chemical defense.
Other Notes
Contains approx. 1 mg protein
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Certificates of Analysis (COA)
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Urease, a nickel-dependent metalloenzyme, is synthesized by plants, some bacteria, and fungi. It catalyzes the hydrolysis of urea into ammonia and carbon dioxide. Although the amino acid sequences of plant and bacterial ureases are closely related, some biological activities differ
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