P5638
L-α-Phosphatidylcholine
from soybean, Type II-S, 14-29% choline basis
Synonym(s):
1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
Recommended Products
biological source
soybean
Quality Level
type
Type II-S
form
powder or solid
concentration
14-29% (choline)
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
2-8°C
InChI
1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChI key
JLPULHDHAOZNQI-ZTIMHPMXSA-N
Looking for similar products? Visit Product Comparison Guide
Related Categories
General description
P5638 is a crude extract of soybean phospholipids.
Typical lots of purified soybean phosphatidylcholine have fatty acid contents of approximately 13% C16:0 (palmitic), 4% C18:0 (stearic), 10% C18:1(oleic), 64% C18:2 (linoleic), and 6% 18:3 (linolenic) with other fatty acids being minor contributors. This would calculate to an average molecular weight of approximately 776.
Purified phosphatidylcholine is soluble in chloroform and ethanol.
Other major phospholipid components include phosphatidylethanolamine and inositol phosphatides. Other phospholipids and neutral lipids such as triglycerides, tocopherols, and sterols may be present. Carbohydrates may also be present.
A procedure for determination of the amount of oxidation of egg phosphatidylcholine in a liposome preparation by measurement of the oxidation index has been published. The oxidation index is the ratio of the absorbance at 233 nm to the absorbance at 215 nm. The latter wavelength was chosen since there is little contribution of the fatty acid carbonyl to the absorbance at this wavelength, allowing Beer′s Law to be followed.
A method of determining choline content has been published.
Typical lots of purified soybean phosphatidylcholine have fatty acid contents of approximately 13% C16:0 (palmitic), 4% C18:0 (stearic), 10% C18:1(oleic), 64% C18:2 (linoleic), and 6% 18:3 (linolenic) with other fatty acids being minor contributors. This would calculate to an average molecular weight of approximately 776.
Purified phosphatidylcholine is soluble in chloroform and ethanol.
Other major phospholipid components include phosphatidylethanolamine and inositol phosphatides. Other phospholipids and neutral lipids such as triglycerides, tocopherols, and sterols may be present. Carbohydrates may also be present.
A procedure for determination of the amount of oxidation of egg phosphatidylcholine in a liposome preparation by measurement of the oxidation index has been published. The oxidation index is the ratio of the absorbance at 233 nm to the absorbance at 215 nm. The latter wavelength was chosen since there is little contribution of the fatty acid carbonyl to the absorbance at this wavelength, allowing Beer′s Law to be followed.
A method of determining choline content has been published.
Biochem/physiol Actions
Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells. In addition to being the major structural component of cellular membranes, phosphatidylcholine serves as a reservoir for several lipid messengers. It is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet activating factor, and arachidonic acid.
Phosphatidylcholine is used for preparation of vesicle suspensions, commonly called liposomes, or as monolayers. Monolayers have been formed using a solution of 1% soybean phosphatidylcholine in hexane.
Valinomycin-induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions have been measured using positively-charged, cyanine dyes that fluorimetrically responded to the change in potential.
Purified rhodopsin has been incorporated into soybean phosphatidylcholine vesicles.
Phosphatidylcholine is used for preparation of vesicle suspensions, commonly called liposomes, or as monolayers. Monolayers have been formed using a solution of 1% soybean phosphatidylcholine in hexane.
Valinomycin-induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions have been measured using positively-charged, cyanine dyes that fluorimetrically responded to the change in potential.
Purified rhodopsin has been incorporated into soybean phosphatidylcholine vesicles.
A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.
Quality
P5638 is a crude soy extract that contains many other lipids.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
R Cassia-Moura et al.
Journal of theoretical biology, 206(2), 235-241 (2000-09-01)
Dynamic activation of ion channels formed by colicin Ia incorporated into a planar bilayer lipid membrane (BLM) was investigated by the voltage clamp technique using different step voltage stimuli. We have demonstrated a critical resting interval, Deltat(c), between two identical
P M Guy et al.
Biochemistry, 29(30), 6954-6964 (1990-07-31)
The intrinsic tryptophan fluorescence of the alpha subunit of transducin (alpha T) has been shown to be sensitive to the binding of guanine nucleotides, with the fluorescence being enhanced by as much as 2-fold upon the binding of GTP or
A simplified and specific method for the estimation of choline.
C J ACKERMAN et al.
Analytical biochemistry, 1, 327-336 (1960-12-10)
Austin J Rice et al.
The Journal of biological chemistry, 288(29), 21228-21235 (2013-05-28)
In bacteria, ATP-binding cassette (ABC) transporters are vital for the uptake of nutrients and cofactors. Based on differences in structure and activity, ABC importers are divided into two types. Type I transporters have been well studied and employ a tightly
Stealth Liposomes
Lasic, D.D. and Martin, F.J. et al.
CRC Press (1995)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service