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Key Documents

P2008

Sigma-Aldrich

Polyanetholesulfonic acid sodium salt

powder

Synonym(s):

Sodium polyanetholesulfonate

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.77

form

powder

Quality Level

storage condition

(Tightly closed. Dry.)

color

yellow

solubility

water: 1 g/10 mL, clear to hazy, yellow to very dark yellow-orange

SMILES string

C/C=C/C1=CC=C(C=C1)OC.[O-]S(=O)[O-].[Na+]

InChI

1S/C10H12O.Na.H2O3S/c1-3-4-9-5-7-10(11-2)8-6-9;;1-4(2)3/h3-8H,1-2H3;;(H2,1,2,3)/q;+1;/p-2/b4-3+;;

InChI key

JKJBFNAERWARKW-CZEFNJPISA-L

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General description

Canonical SMILES: CC=CC1=CC=C(C=C1)OC.[O-]S(=O)[O-].[Na+]

Application

Polyanetholesulfonic acid sodium salt:
  • has been used as a component in BACTEC plus aerobic/F medium or blood culture media to decrease the barrier for bacterial growth
  • has been used to inhibit the activity of classical pathway (CP) and alternative pathway (AP)
  • may be used in the preparation of bifunctional/polymeric composite gel beads to remove cationic dyes

Biochem/physiol Actions

Polyanetholesulfonic acid sodium salt is a polymeric phosphor. It can recognize ferric ion (Fe3+) effectively. Sodium polyanethole sulfonate (SPS) is used in commercial blood culture bottles as an anticoagulant. It can prevent the humoral and cellular elements that might interfere with the growth of bacteria. SPS may influence the complement system. It can block phagocytosis and leukocyte functions.

Other Notes

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Pictograms

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ying Pei et al.
Antiviral research, 89(1), 98-108 (2010-11-27)
To investigate the anti-herpesvirus mechanism of pentagalloylglucose (PGG), we compared the proteomic changes between herpes simplex virus type 1 (HSV-1) infected MRC-5 cells with or without PGG-treatment, and between non-infected MRC-5 cells with or without PGG-treatment by 2-DE and MS-based
Ying Pei et al.
Biochemical and biophysical research communications, 405(2), 186-191 (2011-01-11)
Pentagalloylglucose (PGG) is a natural polyphenolic compound with broad-spectrum anti-viral activity, however, the mechanisms underlying anti-viral activity remain undefined. In this study, we investigated the effects of PGG on anti-viral activity against Herpes simplex virus type 1 (HSV-1) associated with
Xiaojin Qin et al.
RSC advances, 8(54), 31231-31236 (2018-09-04)
Room-temperature phosphorescent materials have been a major focus of research and development during the past decades, due to their applications in OLEDs, photovoltaic cells, chemical sensors, and bioimaging. However, achieving polymeric phosphorescent materials without heavy-metal atoms and halogens under ambient
Damodar Gullipalli et al.
Journal of immunology (Baltimore, Md. : 1950), 210(10), 1543-1551 (2023-03-30)
Complement factor D (FD) is a rate-limiting enzyme of the alternative pathway (AP). Recent studies have suggested that it is synthesized as an inactive precursor and that its conversion to enzymatically active FD is catalyzed by mannan-binding lectin-associated serine protease
A Athamna et al.
FEMS immunology and medical microbiology, 15(2-3), 135-141 (1996-09-01)
The human pathogen Mycoplasma pneumoniac causes primary atypical-cold agglutinin-positive pneumonia. Since alveolar macrophages internalize mycoplasma as part of their immune defense, we studied characteristics of the human macrophage receptor for opsonized and nonopsonized M. pneumoniae. The glass-adhering subpopulation of M.

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