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N0877

Sigma-Aldrich

4-Nitrophenyl α-D-galactopyranoside

α-glucosidase substrate, chromogenic, ≥99% (TLC), powder

Synonym(s):

p-Nitrophenyl α-D-galactopyranoside

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About This Item

Empirical Formula (Hill Notation):
C12H15NO8
CAS Number:
7493-95-0
Molecular Weight:
301.25
Beilstein:
92214
EC Number:
231-343-6
MDL number:
MFCD00065050
UNSPSC Code:
12352204
PubChem Substance ID:
24897448
NACRES:
NA.32
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Product Name

4-Nitrophenyl α-D-galactopyranoside, α-galactosidase substrate

Quality Level

200

Assay

≥99% (TLC)

form

powder

solubility

methanol: 100 mg/mL, clear to very slightly hazy

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9+,10+,11-,12+/m1/s1

InChI key

IFBHRQDFSNCLOZ-IIRVCBMXSA-N

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Application

4-Nitrophenyl α-D-galactopyranoside has been used as a substrate to determine α-galactosidase activity.[1][2][3][4]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3842
WXBD4607V
BCCL6721
WXBF1176V
BCCK4469

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Effects of temperature and relative humidity on growth and enzyme production by Actinomucor elegans and Rhizopus oligosporus during sufu pehtze preparation
Han BZ, et al.
Food Chemistry, 81(1), 27-34 (2003)
Softwood hemicellulose-degrading enzymes from Aspergillus niger: purification and properties of a beta-mannanase
Ademark P, et al.
Journal of Biotechnology, 63(3), 199-210 (1998)
An acetylglucomannan esterase of Aspergillus oryzae; purification, characterization and role in the hydrolysis of O-acetyl-galactoglucomannan
Tenkanen M, et al.
Journal of Biotechnology, 42(3), 197-206 (1995)
In vitro evaluation of feed-grade enzyme activity at pH levels simulating various parts of the avian digestive tract
Ao T, et al.
Anim. Feed Sci. Technol., 140(3-4), 462-468 (2008)
Xuesen Hu et al.
Archiv der Pharmazie, 344(2), 71-77 (2011-02-04)
This experiment was designed to synthesize 18 kinds of polyhydroxybenzophenones by using Friedel-Crafts reaction, and to measure the inhibitory activity on α-glucosidase with p-nitrophenyl-β-D-galactopyranoside (PNPG) as a substrate. Here, acarbose (IC(50)  = 1674.75 µmol L(-1) ) was used as the reference
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