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M1633

Sigma-Aldrich

4-Methylumbelliferyl β-D-galactopyranoside

fluorogenic, ≥99% (TLC), powder

Synonym(s):

MUG, MUGA

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About This Item

Empirical Formula (Hill Notation):
C16H18O8
CAS Number:
6160-78-7
Molecular Weight:
338.31
Beilstein:
94673
EC Number:
228-185-5
MDL number:
MFCD00036773
UNSPSC Code:
12352204
PubChem Substance ID:
24896676
NACRES:
NA.32

product name

4-Methylumbelliferyl β-D-galactopyranoside, ≥99% (TLC)

Quality Level

300

Assay

≥99% (TLC)

form

powder

solubility

pyridine: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13+,14+,15-,16-/m1/s1

InChI key

YUDPTGPSBJVHCN-DZQJYWQESA-N

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General description

4-Methylumbelliferyl β-D-galactopyranoside (MUG) is a UV-absorbing dye that serves as a fluorescent substrate for β-galactosidase in a planar yeast estrogen screen (pYES) for the detection of estrogen active compounds.

Application

4-Methylumbelliferyl β-D-galactopyranoside has been used as a substrate in β-galactosidase activity assay.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yousuke Takaoka et al.
Nature communications, 9(1), 3654-3654 (2018-09-09)
The phytohormone 7-iso-(+)-jasmonoyl-L-isoleucine (JA-Ile) mediates plant defense responses against herbivore and pathogen attack, and thus increases plant resistance against foreign invaders. However, JA-Ile also causes growth inhibition; and therefore JA-Ile is not a practical chemical regulator of plant defense responses.
Mithila Ferdous et al.
Journal of clinical microbiology, 53(11), 3530-3538 (2015-08-28)
The ability of Escherichia coli O157:H7 to induce cellular damage leading to disease in humans is related to numerous virulence factors, most notably the stx gene, encoding Shiga toxin (Stx) and carried by a bacteriophage. Loss of the Stx-encoding bacteriophage
N Khodambashi Emami et al.
Poultry science, 96(9), 3254-3263 (2017-04-30)
This study assessed the effects of 3 commercial organic acid (OA) preparations on growth performance, intestinal morphology, cecal microbiology, and immunity of Escherichia coli K88-challenged (ETEC) broiler chickens. One thousand one-day-old male broiler chickens were divided into 8 treatments of
Karolina Wiśniewska et al.
Gene, 812, 146090-146090 (2021-12-14)
Mucopolysaccharidoses (MPS) are genetic disorders that affect up to 1 in 25,000 births. They are caused by dysfunctions of lysosomal hydrolases that degrade glycosaminoglycans (GAGs) which accumulate in cells, damaging their proper functioning. There are 7 types of MPS, distinguished
Dinah Schick et al.
Journal of chromatography. A, 1497, 155-163 (2017-04-01)
For the planar yeast estrogen screen (pYES), 4-methylumbelliferyl-β-d-galactopyranoside was generally employed as substrate, delivering blue fluorescing 4-methylumbelliferone after enzymatic cleavage by the YES reporter β-d-galactosidase as the positive signal for the presence of estrogen active compounds (EAC). As environmental samples
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