GE17-1287-01

Anx Seph 4 Fast Flow High Sub

Cytiva 17-1287-01, pack of 500 mL

• UNSPSC Code: 47101511
• NACRES: NA.56

Properties

• ligand: diethylaminopropyl
• description: Ion Exchanger Type (value)
• packaging: pack of 500 mL
• manufacturer/tradename: Cytiva 17-1287-01
• matrix: 4% cross-linked agarose
• particle size: 45-165 μm
• average diameter: 90 μm
• cleaning in place: 2-14
• working range: 3-13
• suitability: suitable for bioprocess medium

Description

General description

ANX Sepharose^™ 4 Fast FLow (high sub) is a weak anion exchanger, with a different selectivity compared with traditional ion exchangers. It is optimized for the separation of larger proteins.

Application

ANX Sepharose^™ Fast FLow (high sub) is part of the Sepharose^™ Fast FLow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. ANX Sepharose^™ 4 Fast FLow (high sub) is a weak anion exchanger medium with tertiary amine groups attached to the base matrix Sepharose^™ 4 Fast FLow via ether linkage and a hydrophilic spacer arm. The diethylaminopropylgroup is coupled in a mode that precludes formation of quaternary groups, which are typically seen on traditional DEAE media, resulting in a truly weak anion exchanger. The base matrix, Sepharose^™ 4 Fast Flow, is a highly cross-linked, 4% Agarose derivative with high chemical and physical stability and broad separation range. ANX Sepharose^™ 4 Fast FLow (high sub) has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols.

As member of the BioProcess media range, ANX Sepharose^™ 4 Fast FLow (high sub) meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

• Weak anion exchanger with different selectivity compared with traditional ion exchangers.
• Applicable for separation of high molecular weight Proteins
• Developed in co-operation with leading large-scale pharmaceutical manufacturers
• High chemical stability allows for well proven CIP and sanitization protocols
• The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool.

Storage and Stability

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Store at 4 to 30 °C (20% Ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Sepharose is a trademark of Cytiva

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Statements: H226
• Precautionary Statements: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Storage Class Code: 3 - Flammable liquids