G115080
DMT-dG(dmf) Phosphoramidite
configured for PerkinElmer, configured for Polygen
Synonym(s):
DMT-dG(dmf) Amidite, N-[(dimethylamino)methylene]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N2-Dimethylformamidine-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
About This Item
Recommended Products
type
for DNA synthesis
product line
Proligo Reagents
Assay
≥99% (31P-NMR)
≥99.0% (reversed phase HPLC)
form
powder
technique(s)
oligo synthesis: suitable
color
white to off-white
λ
conforms (UV/VIS Identity)
compatibility
configured for PerkinElmer
configured for Polygen
nucleoside profile
base: deoxyguanosine
base protecting group: DMF
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard
storage temp.
-10 to -25°C
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1 of 4
This Item | G115040 | G115050 | G115060 |
---|---|---|---|
white to off-white | white to off-white | white to off-white | white to off-white |
-10 to -25°C | -10 to -25°C | -10 to -25°C | -10 to -25°C |
for DNA synthesis | for DNA synthesis | for DNA synthesis | for DNA synthesis |
Proligo Reagents | Proligo Reagents | Proligo Reagents | Proligo Reagents |
powder | powder | powder | powder |
General description
- dG(dmf) is deprotected faster than the conventional dG(ib): thedeprotection time in concentrated ammonia is reduced to 2 hours at55 °C or 1 hour at 65 °C
- The dG(dmf)-monomer is especially suitable for G-rich sequences:incomplete deprotection is greatly reduced in comparison with theconventional dG(ib)-monomer
- dG(dmf)-phosphoramidite is as stable in solution as the standard dA(bz)-,dC(bz)- and dT-phosphoramidites
- dG(dmf)-phosphoramidite can directly substitute for dG(ib)-phosphoramidite
- No change is required in the reagents commonly used for DNA synthesis(except a low concentration iodine oxidizer i.e., 0.02 M in iodine, should beemployed)DMT-dG(dmf) Phosphoramidite is configured for Expedite™ and PolyGen® Synthesizers.
Legal Information
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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