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D7782

Sigma-Aldrich

Anti-Digoxin antibody produced in rabbit

whole antiserum

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

radioimmunoassay: 1:10,000

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Immunogen

Digoxin-BSA

Application

Anti-Digoxin antibody produced in rabbit has been used in:
  • fluorescence in situ hybridization (FISH)
  • chromatin immunoprecipitation (ChIP)
  • affinity chromatography

Biochem/physiol Actions

Digoxin is a phytoestrogen that binds estrogen receptors and produces inotropic effects in cardiac muscle. Studies show that digoxin decreases the risk of breast and uterus cancers that are estrogen sensitive.
Digoxin plays an important role in the treatment of heart failure and supraventricular tachyarrhythmias.

Physical form

The product is provided as a undiluted antiserum containing 0.1% sodium azide as a preservative.

Reconstitution

Dilute with buffer: 0.01 M phosphate, pH 7.4, 0.15 M sodium chloride, and 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Establishment and mitotic stability of an extra-chromosomal mammalian replicon
Stehle IM, et al.
BMC Cell Biology, 8(1), 33-33 (2007)
Ivan Vannini et al.
Nature communications, 8(1), 1801-1801 (2017-11-29)
The transcribed ultraconserved regions (T-UCRs) encode long non-coding RNAs implicated in human carcinogenesis. Their mechanisms of action and the factors regulating their expression in cancers are poorly understood. Here we show that high expression of uc.339 correlates with lower survival
Role of Digoxin in Atrial Fibrillation
Scalese MJ, et al.
Journal of Pharmacy Practice, 30(4), 434-440 (2017)
Isolation and characterization of a digoxin-like immunoreactive substance from human urine by affinity chromatography
De Angelis C, et al.
Clinical Chemistry, 43(8), 1416-1420 (1997)
Cell cycle dependent histone dynamics of an episomal non-viral vector
Rupprecht S, et al.
Gene, 439(1-2), 95-101 (2009)

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