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Key Documents

C8056

Sigma-Aldrich

Calf Serum

from formula-fed bovine calves, iron supplemented, USA origin, sterile-filtered, suitable for cell culture

Synonym(s):

bovine calf sera, bovine calf serum, calf sera, calf serum

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About This Item

MDL number:
MFCD00243108
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

bovine (calf) (formula-fed)

Quality Level

500

sterility

sterile-filtered

form

liquid

composition

hemoglobin, ≤35 mg/dL

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

≤10 EU/mL Endotoxin

shipped in

dry ice

storage temp.

−20°C

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Application

Iron-supplemented bovine serum may be used as an alternative to fetal bovine serum in the CHO/HGPRT mutation assay, Oberly, et. al. Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics

Testing Method

Endotoxin tested

Preparation Note

Each lot is supplemented to a constant iron concentration.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rune Busk Damgaard et al.
EMBO molecular medicine, 11(3) (2019-02-26)
The deubiquitinase OTULIN removes methionine-1 (M1)-linked polyubiquitin signals conjugated by the linear ubiquitin chain assembly complex (LUBAC) and is critical for preventing TNF-driven inflammation in OTULIN-related autoinflammatory syndrome (ORAS). Five ORAS patients have been reported, but how dysregulated M1-linked polyubiquitin
Reza Mirnejad et al.
Microbial pathogenesis, 109, 8-14 (2017-05-17)
Brucella is zoonotic pathogen that induces abortion and sterility in domestic mammals and chronic infections in humans called Malta fever. It is a facultative intracellular potential pathogen with high infectivity. The virulence of Brucella is dependent upon its potential virulence
T J Oberly et al.
Mutation research, 244(2), 105-109 (1990-06-01)
Iron-supplemented bovine calf serum (ICS) was found to be a viable alternative to fetal bovine serum (FBS) in the growth promotion and cloning efficiency of Chinese hamster ovary (CHO) cells that are used in the HGPRT mutation assay. Suspension cultures
D R Dahling et al.
Journal of virological methods, 27(3), 287-294 (1990-03-01)
Two studies comparing sewage-isolated and laboratory stock viruses were conducted to determine if alternative forms of serum or serum extenders could be used in place of fetal bovine serum without a significant loss of viral titer. In the first study
S C Thumma et al.
Cancer gene therapy, 22(8), 396-401 (2015-08-01)
Elevated levels of eukaryotic translation initiation factor 4E (eIF4E) enhance translation of many malignancy-related proteins, such as vascular endothelial growth factor (VEGF), c-Myc and osteopontin. In non-small-cell lung cancer (NSCLC), levels of eIF4E are significantly increased compared with normal lung
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