C7602

L-Cystine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonym(s): (R,R)-3,3′-Dithiobis(2-aminopropionicacid)
• Linear Formula: [-SCH₂CH(NH₂)CO₂H]₂
• CAS Number: 56-89-3
• Molecular Weight: 240.30
• Beilstein: 1728094
• EC Number: 200-296-3
• MDL number: MFCD00064228
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24892973
• NACRES: NA.26

Properties

• Product Name: L-Cystine, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
• biological source: non-animal source
• Quality Level: 200
• Agency: meets EP testing specifications
• product line: BioXtra
• Assay: 98.5-101.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white to off-white
• mp: >240 °C (dec.) (lit.)
• solubility: 1 M HCl: 100 mg/mL
• application(s): peptide synthesis
• SMILES string: N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
• InChI key: LEVWYRKDKASIDU-IMJSIDKUSA-N

Description

Application

L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia.[1] It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids.[2]
L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development.[3]

Biochem/physiol Actions

Cystinuria is characterized with renal transport and excretion of L-Cystine.[4] Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine.[5] Reduced availability of cysteine or cystine, influences leukocyte metabolism.[6] L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves