Y0000394
Dipivefrine for system suitability
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
Dipivefrin hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C19H29NO5 · HCl
CAS Number:
Molecular Weight:
387.90
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
dipivefrine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
InChI
1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
InChI key
VKFAUCPBMAGVRG-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Dipivefrine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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A O D'Ostroph et al.
Ophthalmic plastic and reconstructive surgery, 17(5), 328-331 (2001-10-20)
To report patients who presented to the oculoplastics department for repair of cicatrical entropion after topical use of dipivefrin. To discuss the possible mechanisms of action and highlight the potential detrimental effects of dipivefrin on palpebral conjunctiva. Retrospective consecutive noncomparative
Contact dermatitis from dipivefrine with possible cross-reaction to epinephrine.
A Parra et al.
Contact dermatitis, 39(6), 325-326 (1999-01-05)
M R Holdiness
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 12(4), 217-219 (2001-12-26)
A review of the literature has identified 10 agents causing contact dermatitis among topically administered drugs for glaucoma. These agents include beta-blockers (timolol, befunolol, betaxolol, levobunolol, carteolol, metipranolol), a carbonic anhydrase inhibitor (dorzolamide), a parasympathomimetic (pilocarpine), and sympathomimetics (dipivefrin, apraclonidine).
Show-Jen Hong et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 19(3), 205-215 (2003-06-28)
Over releasing of glutamate and cellular calcium influx always results in neuronal death. In the present study, we investigated various commercial antiglaucoma drugs including timolol (0.58 microM to 58 microM), betaxolol (1.62 microM to 162 microM), carteolol (6.8 microM to
D F Edgar et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 237(2), 117-124 (1999-02-13)
A study was carried out to ascertain, in ophthalmologically normal subjects, the short-term effects of dipivefrin hydrochloride 0.1% on visual performance and make comparisons with pilocarpine. Twelve normal volunteers aged 20-26 years attended on three occasions. One eye, randomly selected
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