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Y0000063

Heptaminol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-Amino-2-methyl-2-heptanol hydrochloride, Heptaminol hydrochloride

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About This Item

Linear Formula:
CH3CH(NH2)(CH2)3C(OH)(CH3)2 · HCl
CAS Number:
543-15-7
Molecular Weight:
181.70
Beilstein:
3673011
MDL number:
MFCD00013015
UNSPSC Code:
41116107
PubChem Substance ID:
329830831
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

heptaminol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CC(N)CCCC(C)(C)O

InChI

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H

InChI key

JZNBMCOSOXIZJB-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Heptaminol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Mabrouk Bahloul et al.
American journal of therapeutics, 19(1), e8-17 (2010-08-20)
We analyze in the current study the impact of heptaminol hydrochloride (Heptamyl) administration in patients with septic shock requiring adrenergic support on the duration of vasopressor infusion and on catecholamine delay weaning. In this prospective study were included 49 nonconsecutive
K Ueno et al.
Japanese journal of pharmacology, 52(3), 483-488 (1990-03-01)
Heptaminol AMP amidate (HAA), a nucleotide derivative, was found to elevate the intracellular cyclic AMP (cAMP) level of cultured mice spleen cells in a time- and dose-dependent manner. Theophylline and imidazole, when added to the spleen cell culture simultaneously with
N Peineau et al.
British journal of pharmacology, 107(1), 104-108 (1992-09-01)
1. The effects of heptaminol on calcium current amplitude and characteristics were studied in single ventricular myocytes of guinea-pig by use of the whole cell configuration of the patch clamp technique. 2. A concentration-dependent decrease in ICa amplitude was observed.
P D Drumheller et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 11(5), 1258-1265 (1991-09-01)
An endothelial cell monolayer with a single mechanically lysed cell was used as a model to examine the extent, kinetics, and nature of local calcium mobilization in the neighborhood of a wound. Individual endothelial cells from confluent monolayers were mechanically
B Pourrias
Annales pharmaceutiques francaises, 49(3), 127-138 (1991-01-01)
Heptaminol hydrochloride is widely used for the treatment for orthostatic hypotension. It continues to elicit controversy as to its mode of action since Loubatières (1951) described its powerful inotropic action on an ischaemic preparation. Twenty five years later it has
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