Skip to Content
Merck

B0301

Sigma-Aldrich

Biotin

meets USP testing specifications

Synonym(s):

D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
EC Number:
MDL number:
UNSPSC Code:
12352201
eCl@ss:
34058011
PubChem Substance ID:
NACRES:
NA.21

Pricing and availability is not currently available.

biological source

synthetic (organic)

Quality Level

Agency

meets USP testing specifications

Assay

97.5-102.0%

form

powder

color

white

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
19606PHR123391827
Biotin meets USP testing specifications

B0301

Biotin

Biotin tested according to Ph. Eur.

19606

Biotin

Biotin Pharmaceutical Secondary Standard; Certified Reference Material

PHR1233

Biotin

Biotin certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

91827

Biotin

assay

97.5-102.0%

assay

-

assay

-

assay

-

form

powder

form

-

form

-

form

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

clinical testing
pharmaceutical (small molecule)

storage temp.

2-8°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

300

Application

<ul>
<li><strong>Protein Biotinylation Studies:</strong> Advanced strategies for biotinylation site characterization in proteins are being developed using biotin, improving the precision of protein modification techniques critical for biochemical research and drug development (Zhu, 2024).</li>
</ul>

Biochem/physiol Actions

Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Konstantinos Ampatzis et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(26), 10875-10886 (2013-06-28)
In vertebrates, spinal circuits drive rhythmic firing in motoneurons in the appropriate sequence to produce locomotor movements. These circuits become active early during development and mature gradually to acquire the flexibility necessary to accommodate the increased behavioral repertoire of adult
Stuart Trenholm et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14927-14938 (2013-09-13)
Recently, we demonstrated that gap junction coupling in the population of superior coding ON-OFF directionally selective ganglion cells (DSGCs) genetically labeled in the Hb9::eGFP mouse retina allows the passage of lateral anticipatory signals that help track moving stimuli. Here, we
Adeline Huiling Loo et al.
Nanoscale, 5(17), 7844-7848 (2013-07-13)
Graphene related materials have been widely employed as highly efficient transducers for biorecognition. Here we show a conceptually new approach of using graphene oxide nanoplatelets (50 × 50 nm) as voltammetric inherently active labels for specific protein-target molecule recognition. This
Tuncay Baubec et al.
Cell, 153(2), 480-492 (2013-04-16)
To gain insight into the cellular readout of DNA methylation, we established a strategy for systematically profiling the genome-wide distribution of chromatin-interacting factors. This enabled us to create genomic maps for the methyl-CpG-binding domain (MBD) family of proteins, including disease-relevant
John J Tukker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(16), 6809-6825 (2013-04-19)
Hippocampal CA3 area generates temporally structured network activity such as sharp waves and gamma and theta oscillations. Parvalbumin-expressing basket cells, making GABAergic synapses onto cell bodies and proximal dendrites of pyramidal cells, control pyramidal cell activity and participate in network

Articles

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service