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Supelco

Palmitic acid

analytical standard

Synonym(s):

1-Pentadecanecarboxylic acid, C16:0, Cetylic acid, Hexadecanoic acid, NSC 5030, PamOH

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About This Item

Linear Formula:
CH3(CH2)14COOH
CAS Number:
57-10-3
Molecular Weight:
256.42
Beilstein:
607489
EC Number:
200-312-9
MDL number:
MFCD00002747
UNSPSC Code:
85151701
PubChem Substance ID:
329766912
NACRES:
NA.24

grade

analytical standard

Quality Level

100

vapor pressure

10 mmHg ( 210 °C)

Assay

≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

271.5 °C/100 mmHg (lit.)

mp

61-62.5 °C (lit.)

density

0.852 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

functional group

carboxylic acid

shipped in

ambient

storage temp.

room temp

SMILES string

CCCCCCCCCCCCCCCC(O)=O

InChI

1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)

InChI key

IPCSVZSSVZVIGE-UHFFFAOYSA-N

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General description

Palmitic acid belongs to the group of saturated fatty acids and accounts for 20-30 % of the total fatty acids present in the human body.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

This analytical standard can also be used as follows:
  • Development of a non-destructive Vis-NIR reflectance spectroscopy-based method for the detection of four fatty acids in 93 samples of seven different edibles oils
  • Simultaneous identification and quantification of fatty acids from blood plasma samples after their methyl derivatization by large-volume injection (LVI) gas chromatography combined with vacuum ultraviolet spectroscopy (GC-VUV)
  • Determination of the fatty acid composition of sunflower seed oils extracted from 93 different sunflower varieties by near-infrared reflectance spectroscopy (NIRS) combined with modified partial least squares (MPLS) and partial least squares (PLS) regression methods
  • Separation and quantification of palmitic, oleic, linoleic, and linolenic acids from 186 samples of sea buckthorn seed oil using near-infrared spectroscopy (NIR) in combination with four different combinations of multivariate calibration methods— partial least squares (PLS), PLS-uninformative variables elimination (UVE), PLS- competitive adaptive reweighted sampling (CARS), and multiple linear regression (MLR)-UVE
  • Quantitative analysis of various bioactive compounds from the ethanolic extract of sesame seeds by gas chromatography-mass spectrometry (GC-MS)
  • Multi-residue analysis of oleic acid and other related fatty acids using a derivatization-free method based on gas chromatography-flame ionization detection (GC-FID)
  • Ultra-performance liquid chromatography-mass spectrometry (UHPLC) method-based separation, identification, and determination of eight saturated and unsaturated fatty acids in eight different commercial samples of olive oil without any prior sample treatment
  • Development of a liquid chromatography-mass spectrometry (LC-MS) method to measure seven fatty acid esters of hydroxy fatty acids (FAHFAs), four fatty acids, and four cardiovascular-related biomarkers in plasma samples of 57 healthy individuals

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCK4673
BCCH2916
BCCF7096
BCCB6616
BCBX4516

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Impact of myristic acid versus palmitic acid on serum lipid and lipoprotein levels in healthy women and men
Zock LP, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 14(4), 567-575 (1994)
Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry
Takashima S, et al.
Molecular Genetics and Metabolism, 120(3), 255-268 (2017)
Jonas Sieber et al.
The American journal of pathology, 183(3), 735-744 (2013-07-23)
Type 2 diabetes mellitus is characterized by dyslipidemia with elevated free fatty acids (FFAs). Loss of podocytes is a hallmark of diabetic nephropathy, and podocytes are highly susceptible to saturated FFAs but not to protective, monounsaturated FFAs. We report that
B Vessby et al.
Diabetologia, 37(10), 1044-1050 (1994-10-01)
Recent data indicate that peripheral insulin sensitivity may be influenced by dietary fat quality and skeletal muscle phospholipid fatty acid composition. During a health survey of 70-year-old men insulin sensitivity was measured by the euglycaemic hyperinsulinaemic clamp technique and the
Li Liu et al.
Experimental neurology, 248, 482-490 (2013-08-24)
Deregulation of calcium has been implicated in neurodegenerative diseases, including Alzheimer's disease (AD). Previously, we showed that saturated free-fatty acid, palmitate, causes AD-like changes in primary cortical neurons mediated by astrocytes. However, the molecular mechanisms by which conditioned medium from
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