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Cimaterol

VETRANAL®, analytical standard

Synonym(s):

2-Amino-5-(1-hydroxy-2-isopropylaminoethyl)benzonitrile

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About This Item

Empirical Formula (Hill Notation):
C12H17N3O
CAS Number:
54239-37-1
Molecular Weight:
219.28
Beilstein:
2418129
MDL number:
MFCD00209815
UNSPSC Code:
41116107
PubChem Substance ID:
329754032
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

CC(C)NCC(O)c1ccc(N)c(c1)C#N

InChI

1S/C12H17N3O/c1-8(2)15-7-12(16)9-3-4-11(14)10(5-9)6-13/h3-5,8,12,15-16H,7,14H2,1-2H3

InChI key

BUXRLJCGHZZYNE-UHFFFAOYSA-N

General description

Cimaterol is a β-adrenergic agonist.
Cimaterol is classified under the β-agonist class of drugs.

Application

Cimaterol may be used as a reference standard for the determination of the analyte in animal tissues, feeding-stuffs, and feces by high-performance liquid chromatography and post-column derivatization.
Cimaterol may be used as an analytical reference standard for the determination of the analyte in:
  • Feed samples by solid-phase extraction (SPE) and ultra-performance liquid chromatography (UPLC).
  • Pig liver, kidney and muscle samples by SPE and UPLC coupled to tandem mass spectrometry (MS/MS).
  • Bovine retina by SPE and gas chromatography-mass spectrometry (GC-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK4845
BCCG4631
BCCF3225
BCCB8599
BCBX0034

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Gas chromatography-mass spectrometry analysis of β2-agonists in bovine retina.
Hernandez-Carrasquilla M
Analytica Chimica Acta, 408(1-2), 285-290 (2000)
G Van Vyncht et al.
Journal of chromatography. A, 750(1-2), 43-49 (1996-10-25)
beta-Agonists are substances used in veterinary and human medicine for the treatment of pulmonary disorders. They have found a use as growth promoters to improve meat-to-fat ratios in cattle but they are not authorized for use in the European Union.
B L Gwartney et al.
Journal of animal science, 70(7), 2144-2150 (1992-07-01)
The response time to cimaterol (CIM), a beta-adrenergic agonist, by broiler chickens for carcass characteristics, muscle composition, muscle fiber size, catheptic enzyme activity, and tenderness was determined. Two trials were conducted in which chickens were fed a control diet (CON)
High-performance liquid chromatographic determination of clenbuterol and cimaterol using post-column derivatization.
Courtheyn D, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 564(2), 537-549 (1991)
T M Byrem et al.
Journal of animal science, 76(4), 988-998 (1998-05-15)
Our objective was to determine whether the chronic anabolic effects of beta-adrenergic agonists on skeletal muscle are direct and how long they are maintained. We studied acute (6 h) and chronic (1 to 20 d) effects of cimaterol (CIM) on
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Determination of 11 Beta Agonist Residues in Pork by LC-MS

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Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

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