240486

2-Methyl-2-butanol

ReagentPlus^®, ≥99%

• Synonym(s): tert-Amyl alcohol, tert-Pentyl alcohol
• Linear Formula: CH₃CH₂C(CH₃)₂OH
• CAS Number: 75-85-4
• Molecular Weight: 88.15
• Beilstein: 1361351
• EC Number: 200-908-9
• MDL number: MFCD00004478
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854418
• NACRES: NA.21

Properties

• vapor density: 3 (vs air)
• Quality Level: 100
• vapor pressure: 12 mmHg ( 20 °C)
• product line: ReagentPlus^®
• Assay: ≥99%
• form: liquid
• autoignition temp.: 819 °F
• expl. lim.: 9 %
• refractive index: n20/D 1.405 (lit.)
• bp: 102 °C (lit.)
• mp: −12 °C (lit.)
• density: 0.805 g/mL at 25 °C (lit.)
• functional group: hydroxyl
• SMILES string: CCC(C)(C)O
• InChI: 1S/C5H12O/c1-4-5(2,3)6/h6H,4H2,1-3H3
• InChI key: MSXVEPNJUHWQHW-UHFFFAOYSA-N

Description

General description

2-Methyl-2-butanol is a sterically hindered alcohol.

Application

2-Methyl-2-butanol may be used as a solvent in the following processes:

• Palladium (II)-catalyzed ortho-C–H olefination of phenylacetic acids.
• Rhodium-catalyzed direct C-H functionalization at the C7 position of N-pivaloylindoles.

It may also be used in the preparation of 2-chloro-2-methylbutane by reacting with concentrated hydrochloric acid.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H312 + H332,H315,H318,H335,H336
• Precautionary Statements: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 68.9 °F - closed cup
• Flash Point(C): 20.5 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves