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Key Documents

SKBM02560

Millipore

PES Membrane Filter

Strat-M®, filter diam. 25 mm

Synonym(s):

PES membrane for transdermal diffusion testing, Polyethersulfone Strat-M membrane, Strat-M® Membrane, Transdermal Diffusion Test Model, 25mm

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About This Item

UNSPSC Code:
40161507
eCl@ss:
32160907
NACRES:
NB.24

material

plain filter
polyethersulfone membrane (synthetic lipid post-treatment)
polyolefin membrane (synthetic lipid post-treatment)
white filter

Quality Level

sterility

non-sterile

manufacturer/tradename

Millipore
Strat-M®

filter diam.

25 mm

thickness

300 μm

shipped in

ambient

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General description

Filter Code: SKBM
Strat-M Membrane for Transdermal Diffusion Testing
Experience the unmatched predictability of Strat-M membrane – a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Strat-M membrane is designed for screening of:
•Active pharmaceutical ingredients (API)
•Cosmetic actives
•Formulations
•Personal care products
•Pesticides and chemicals

Human Skin Correlation
Strat-M membrane is predictive of diffusion in human skin for a wide range of compounds and formulations. Use the Compound Correlation Tool to learn how well Strat-M membrane will work for you.

Reproducible Diffusion Data:
No need to repeat testing each time a new lot of skin arrives in the lab. Strat-M membrane is a highly consistent, engineered material that allows you to compare today’s diffusion data with data you will generate next week, or next month. Furthermore, lot-to-lot consistency brings a new level of clarity to your test data, simplifying your analysis.

Sensitive to Enhancers
Strat-M membrane exhibits differential permeability in the presence of enhancers and is compatible with common formulation formats, so it is appropriate for use during formulation optimization.

Ultimate Experimental Convenience
Strat-M membrane was designed with convenience in mind. The Strat-M membrane is shelf-stable and stocked in the warehouse so procurement and storage is a breeze. Each membrane is individually packaged as precut discs and do not need to be hydrated prior to use. Simply remove the Strat-M membrane disc from its pouch and load into a Franz cell.

Application

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

Legal Information

STRAT-M is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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PREDICTION OF SKIN PERMEATION BY CHEMICAL COMPOUNDS USING THE ARTIFICIAL MEMBRANE, STRAT-M?
Uchida T, Kadhum WR, Kanai S, Todo H, Oshizaka T, Sugibayashi K
European Journal of Pharmaceutical Sciences null
CURCUMIN-EUDRAGIT? E PO SOLID DISPERSION: A SIMPLE AND POTENT METHOD TO SOLVE THE PROBLEMS OF CURCUMIN.
Li J, Lee IW, Shin GH, Chen X, Park HJ.
European Journal of Pharmaceutics and Biopharmaceutics null
Tai-Long Pan et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 65, 105-114 (2014-01-05)
The toxicity of phthalates is an important concern in the fields of environmental health and toxicology. Dermal exposure via skin care products, soil, and dust is a main route for phthalate delivery. We had explored the effect of topically-applied phthalates
IN VITRO SKIN MODELS AS A TOOL IN OPTIMIZATION OF DRUG FORMULATION.
Flaten GE, Palac Z, Engesland A, Filipovic-Grcic J, Vanic Z, Skalko-Basnet N
European Journal of Pharmaceutical Sciences null
Membrane properties for permeability testing: Skin versus synthetic membranes
Haq A, Dorrani M, Goodyear B, Joshi V, Michniak-Kohn B.
International Journal of Pharmaceutics null

Articles

Strat-M synthetic membrane model is an alternative to human skin for testing the effectiveness of skin care actives.

Strat-M synthetic membrane model is an alternative to human skin for testing the effectiveness of skin care actives.

Strat-M synthetic membrane model is an alternative to human skin for testing the effectiveness of skin care actives.

Strat-M synthetic membrane model is an alternative to human skin for testing the effectiveness of skin care actives.

Protocols

Step-by-step protocol and video for transdermal diffusion testing using Strat-M® synthetic skin membranes.

Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

Related Content

Strat-M® membrane offers consistent transdermal diffusion testing, ensuring reliable data for comparative analysis over time.

Strat-M® membrane offers consistent transdermal diffusion testing, ensuring reliable data for comparative analysis over time.

Strat-M® membrane offers consistent transdermal diffusion testing, ensuring reliable data for comparative analysis over time.

Strat-M® membrane offers consistent transdermal diffusion testing, ensuring reliable data for comparative analysis over time.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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