This product is intended for research use only as an analytical standard. The solvent used to prepare this standard is acetonitrile which is not suitable for use in tissue culture or animal models.
E-060
17β-Estradiol solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C18H24O2
CAS Number:
Molecular Weight:
272.38
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
clinical testing
format
single component solution
storage temp.
2-8°C
SMILES string
CC12CCC3C(CCc4cc(O)ccc34)C1CCC2O
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
Gene Information
human ... ESR1(2099)
General description
A Certified Spiking Solution® suitable for use as starting material in calibrators, controls, or linearity standards for a variety of LC/MS or GC/MS applications from endocrinology to clinical and diagnostic testing.
17β-Estradiol belongs to the group of endogenous endocrine disruptors that disturb thyroid activity and function. It is also a sex hormone prescribed under the trade names Vagifem®, Estring®, Evamist, Elestrin®, Estrace®, and Estrogel® as a treatment for hypoestrogenism.
17β-Estradiol belongs to the group of endogenous endocrine disruptors that disturb thyroid activity and function. It is also a sex hormone prescribed under the trade names Vagifem®, Estring®, Evamist, Elestrin®, Estrace®, and Estrogel® as a treatment for hypoestrogenism.
Application
The Certified Reference Material (CRM) in solution can also be used as follows:
- Electrochemical determination of 17β-Estradiol in river water samples using a reduced graphene oxide and a metal complex porphyrin-based sensor
- Development of a fluorescence resonance energy transfer (FRET) based aptasensor to determine 17β-Estradiol in environmental water, urine, and milk samples
- Analysis of milk product samples to estimate 17β-Estradiol by high-performance liquid chromatography (HPLC) coupled with fluorescence detection following its solid phase extraction using graphene/multi-walled carbon nanotubes (MWCNTs)
- Solid phase extraction of 17β-estradiol and 17α-ethinylestradiol from tap water samples using magnetic graphene oxide (GO)/γ-Fe2O3 nanoparticles for their simultaneous quantification by high-performance liquid chromatography (HPLC) combined with fluorescence detector
- Multi-residue analysis of 17β-estradiol and 17α-ethinylestradiol in commercial pharmaceutical formulation and urine samples using hanging mercury drop electrode and screen printed carbon electrode
Features and Benefits
- Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
- Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
- Rigorously tested through real-time stability studies to ensure accuracy and shelf life
- Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
- Flame sealed under argon into ampoules for long-term shelf life
- Offered in a convenient, DEA-exempt format to improve laboratory efficiency
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Elestrin is a registered trademark of Azur Pharma
Estrace is a registered trademark of Warner Chilcott Company, LLC
Estring is a registered trademark of Pfizer Health AB
Estrogel is a registered trademark of Ascend Therapeutics, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vagifem is a registered trademark of Novo Nordisk A/S Corp.
related product
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
35.6 °F - closed cup
Flash Point(C)
2 °C - closed cup
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Hirotaka Ishii et al.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 13(4), 323-334 (2007-07-24)
It is believed that sex hormones are synthesized in the gonads and reach the brain via the blood circulation. In contrast with this view, the authors have demonstrated that sex hormones are also synthesized locally in the hippocampus and that
Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions.
S Safe
Vitamins and hormones, 62, 231-252 (2001-05-11)
Estrogen receptor-alpha (ER alpha) is a ligand-activated transcription factor and a member of the nuclear receptor superfamily. The classic mechanism of ER alpha action is associated with estrogen-induced formation of a nuclear ER alpha homodimer, binding to 5'-regulatory estrogen response
William Rosner et al.
The Journal of clinical endocrinology and metabolism, 98(4), 1376-1387 (2013-03-07)
The objective of the study was to evaluate the current state of clinical assays for estradiol in the context of their applications. The participants were appointed by the Council of The Endocrine Society and charged with attaining the objective using
Angelo Di Leo et al.
Journal of the National Cancer Institute, 106(1), djt337-djt337 (2013-12-10)
At the time of the initial analysis of overall survival (OS) for the Comparison of Faslodex in Recurrent or Metastatic Breast Cancer (CONFIRM) randomized, double-blind, phase III trial, approximately 50% of patients had died. A final analysis of OS was
Michael J Gibney et al.
The American journal of clinical nutrition, 82(3), 497-503 (2005-09-13)
Metabolomics has been widely adopted in pharmacology and toxicology but is relatively new in human nutrition. The ultimate goal, to understand the effects of exogenous compounds on human metabolic regulation, is similar in all 3 fields. However, the application of
-
これはヒトのエストラジオールで間違いないでしょうか？ また、これをマウスなどに投与した際、マウスのエストロゲン受容体に対しては効果は出ないのでしょうか？
1 answer-
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
