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Key Documents

P2880

Sigma-Aldrich

Propionylthiocholine iodide

≥98%

Synonym(s):

(2-Mercaptoethyl)trimethylammonium iodide propionate

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About This Item

Linear Formula:
C8H18NOSI
CAS Number:
Molecular Weight:
303.20
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

form

powder

mp

200-202 °C (lit.)

storage temp.

−20°C

SMILES string

[I-].CCC(=O)SCC[N+](C)(C)C

InChI

1S/C8H18NOS.HI/c1-5-8(10)11-7-6-9(2,3)4;/h5-7H2,1-4H3;1H/q+1;/p-1

InChI key

BJQIXLJDWWVGAE-UHFFFAOYSA-M

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Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Patricia G Rodrigues et al.
American journal of physiology. Heart and circulatory physiology, 316(3), H459-H475 (2018-12-12)
Several studies have demonstrated that administration of doxorubicin (DOXO) results in cardiotoxicity, which eventually progresses to dilated cardiomyopathy. The present work aimed to evaluate the early myocardial changes of DOXO-induced cardiotoxicity. Male New Zealand White rabbits were injected intravenously with
J M Monserrat et al.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 120(2), 193-199 (1998-11-25)
In this study, some kinetic and toxicological parameters of the thoracic ganglia cholinesterase from the estuarine crab Chasmagnathus granulata were determined. Effects of the type and concentration of substrate, pH (6.80-8.50), incubation temperature (5-35 degrees C) and eserine on the
R N Guedes et al.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 119(2), 205-210 (1998-07-21)
Acetylcholinesterase (AChE, EC 3.1.1.7) purified from the lesser grain borer (Rhyzopertha dominica) was significantly inhibited by higher concentrations of the substrates acetylthiocholine (ATC), acetyl-(beta-methyl) thiocholine (A beta MTC) and propionylthiocholine (PTC). 2. The efficiency of AChE for hydrolyzing different substrates
Andrea Mosca et al.
Clinical chemistry and laboratory medicine, 41(3), 317-322 (2003-04-23)
No comparative information is available concerning the ability of various cholinesterase (ChE) methods to identify succinyldicholine-sensitive patients, purely on the basis of the enzyme activity recorded in serum. Here, we evaluated six different methods for the measurement of ChE activity;
Magda A Mohamed et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 146(3), 314-324 (2007-05-29)
Acetylcholinesterases (AChEs) have been estimated in the infective juveniles (IJs) of eight different strains of heterorhabditid nematodes. The enzyme content ranged from 45.6 to 421.3 units/10(5) IJs with specific activity 34.0 to 82.6 units/mg protein. The isoenzyme patterns revealed the

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