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F2003

Sigma-Aldrich

Flavone

≥99.0%

Synonym(s):

2-Phenyl-4H-1-benzopyran-4-one, 2-Phenylchromone

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About This Item

Empirical Formula (Hill Notation):
C15H10O2
CAS Number:
525-82-6
Molecular Weight:
222.24
Beilstein:
157598
EC Number:
208-383-8
MDL number:
MFCD00006825
UNSPSC Code:
12352100
PubChem Substance ID:
57654180
NACRES:
NA.22

Quality Level

200

Assay

≥99.0%

form

powder

mp

94-97 °C (lit.)

SMILES string

O=C1C=C(Oc2ccccc12)c3ccccc3

InChI

1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H

InChI key

VHBFFQKBGNRLFZ-UHFFFAOYSA-N

Gene Information

human ... ADORA3(140) , ANPEP(290) , CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Adora1(29290) , Adora2a(25369) , Ar(24208) , Gabra2(29706)

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000401483
0000401483
0000330552
0000330551
SLCR3516

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Sigma-Aldrich

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trans-Chalcone

Aaron Ciechanover et al.
Experimental & molecular medicine, 47, e147-e147 (2015-03-15)
Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the UPS, in which Ub-conjugated substrates are deubiquitinated, unfolded and cleaved
León Jesús German-Ponciano et al.
Neurochemistry international, 140, 104850-104850 (2020-09-23)
Chrysin (5,7-dihydroxyflavone), a nutraceutical flavonoid present in diverse plants, has a backbone structure shared with the flavone backbone, with additional hydroxyl groups that confers its antioxidant properties and effects at the GABAA receptor complex. However, whether these effects are due
Daria Nitarska et al.
BMC plant biology, 18(1), 216-216 (2018-10-05)
Commercially available poinsettia (Euphorbia pulcherrima) varieties prevalently accumulate cyanidin derivatives and show intense red coloration. Orange-red bract color is less common. We investigated four cultivars displaying four different red hues with respect to selected enzymes and genes of the anthocyanin
Yu-Wan Ni et al.
Plants (Basel, Switzerland), 9(5) (2020-05-21)
Functional constituents in the leaves of Passiflora plants contain antidepressant and antianxiety effects which are beneficial to human health and fitness. The objective of this study was to investigate leaf growth, physiological parameters, and secondary metabolite contents of Tainung No.
Xiaodan Zhao et al.
Water research, 119, 126-135 (2017-04-30)
The kinetics for the reactions of hypoiodous acid (HOI) with various phenols (phenol, 4-nitrophenol, 4-hydroxybenzoic acid), 3-oxopentanedioic acid (3-OPA) and flavone were investigated in the pH range of 6.0-11.0. The apparent second order rate constants for the reactions of HOI
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