901219

VPhos Pd G3

95%

• Empirical Formula (Hill Notation): C₄₆H₆₂NO₄PPdS
• Molecular Weight: 862.45
• UNSPSC Code: 12161600
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 95%
• form: powder or crystals
• feature: generation 3
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings
• functional group: phosphine

Description

Application

Buchwald palladacycle precatalyst with new biaryl(dialkyl)phosphine ligand, VPhos, has an improved activity profile for the reductive coupling of non-aromatic heterocyclic alkyl bromides. Its combined use with a surfactant system of octanoic acid/sodium octanoate enables Negishi coupling and access to diverse C(sp³)–C(sp²) cross-coupled products.

Other Notes

An Improved System for the Aqueous Lipshutz–Negishi Cross-Coupling of Alkyl Halides with Aryl Electrophiles

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable