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62840

Sigma-Aldrich

L-Lysine

≥98.0% (NT), for peptide synthesis

Synonym(s):

(S)-2,6-Diaminocaproic acid

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About This Item

Linear Formula:
H2N(CH2)4CH(NH2)CO2H
CAS Number:
Molecular Weight:
146.19
Beilstein:
1722531
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

product name

L-Lysine, crystallized, ≥98.0% (NT)

Quality Level

Assay

≥98.0% (NT)

form

solid

optical activity

[α]20/D +26.0±1.0°, c = 2% in 6 M HCl

quality

crystallized

reaction suitability

reaction type: solution phase peptide synthesis

impurities

≤1% water

mp

215 °C (dec.) (lit.)
~215 °C (dec.)

solubility

H2O: 0.1 g/mL, clear, colorless to very faintly greenish-yellow

application(s)

peptide synthesis

SMILES string

NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

InChI key

KDXKERNSBIXSRK-YFKPBYRVSA-N

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General description

L-lysine is an amino acid commonly used as a building block in solid-phase peptide synthesis (SSPS).

Application

L-lysine serves as a precursor in the formation of polymeric structures.It is also used for the synthesis and modification of chitosan resin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Fluorescent labeling of peptides on solid phase
AR Katritzky, et al.
Organic & Biomolecular Chemistry, 6, 4582-4586 (2008)
Adsorption of platinum (IV), palladium (II) and gold (III) from aqueous solutions onto l-lysine modified crosslinked chitosan resin
K Fujiwara et al.
Journal of Hazardous Materials, 146, 39-50 (2007)
Hierarchical nanofabrication of microporous crystals with ordered mesoporosity.
Fan W
Nature Materials, 7(12), 984-984 (2008)
Modulating the poly-l-lysine structure through the control of the protonation--deprotonation state of l-lysine
L Stagi, et al.
Scientific Reports, 12, 19719-19719 (2022)
Sofia Faraasen et al.
Pharmaceutical research, 20(2), 237-246 (2003-03-15)
The purpose of this study was to demonstrate specific receptor-mediated targeting of phagocytes by functional surface coatings of microparticles, shielding from nonspecific phagocytosis and allowing ligand-specific interactions via molecular recognition. Coatings of the comb polymer poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG) were investigated

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