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461814

Sigma-Aldrich

5-Bromosalicylic acid

technical grade, 90%

Synonym(s):

5-Bromo-2-hydroxybenzoic acid

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About This Item

Linear Formula:
BrC6H3-2-(OH)CO2H
CAS Number:
Molecular Weight:
217.02
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

Assay

90%

form

solid

mp

159-162 °C (lit.)

functional group

bromo
carboxylic acid

SMILES string

OC(=O)c1cc(Br)ccc1O

InChI

1S/C7H5BrO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11)

InChI key

IEJOONSLOGAXNO-UHFFFAOYSA-N

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General description

5-Bromosalicylic acid is a salicylic acid derivative. Its bonding to viscose fabric can impart antibacterial properties to the fabric. It has been identified as one of the brominated disinfection byproduct (Br-DBP) formed during the chlorination of saline sewage effluents.

Application

5-Bromosalicylic acid may be employed as a starting reagent for the synthesis of honokiol, a biphenyl-type neolignan.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Tomoyuki Esumi et al.
Bioorganic & medicinal chemistry letters, 14(10), 2621-2625 (2004-04-28)
Honokiol, a biphenyl-type neolignan, which shows the remarkable neurotrophic effect in primary cultured rat cortical neurons, has been effectively synthesized in 21% yield over 14 steps starting from 5-bromosalicylic acid and p-hydroxybenzoic acid by utilizing Pd-catalyzed Suzuki-Miyaura coupling reaction as
Yi Wang et al.
Analytica chimica acta, 1002, 97-104 (2018-01-08)
Seed-mediated growth has been employed as a simple and powerful means to the shape-controlled synthesis of metal nanocrystals. In this work, we apply the principle of seed-mediated growth in analytical chemistry, and achieve improved sensitivity due to the low energy
Jian Zhu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 236, 118343-118343 (2020-04-18)
Au@AuAg yolk-shell nanorods with tunable and uniform interior gap were synthesized through galvanic replacement reaction, where Au@Ag core-shell nanorods served as sacrificial templates and HAuCl4 solution served as reductant. The effects of HAuCl4, Ag shell thickness and aspect ratio (AR)
Hongrui Cheng et al.
Nanoscale, 12(17), 9471-9480 (2020-04-30)
Highly flexible and stable plasmonic nanopaper comprised of silver nanocubes and cellulose nanofibres was fabricated through a self-assembly-assisted vacuum filtration method. It shows significant enhancement of the fluorescence emission with an enhancement factor of 3.6 and Raman scattering with an
Álvaro Cárcamo-Martínez et al.
Nanomaterials (Basel, Switzerland), 10(3) (2020-03-27)
Current strategies for the treatment of superficial non-melanoma skin cancer (NMSC) lesions include topical imoquimod, 5-fluorouracil, and photodynamic therapy. Although these treatments are effective, burning pain, blistering, and dermatitis have been reported as frequent side effects, making these therapies far

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