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38950

Sigma-Aldrich

Dimethylamine solution

purum, 33% in absolute ethanol (~5.6 M)

Synonym(s):

N,N-Dimethylamine

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About This Item

Linear Formula:
(CH3)2NH
CAS Number:
Molecular Weight:
45.08
Beilstein:
605257
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:
NACRES:
NA.22

grade

purum

Quality Level

form

liquid

concentration

32-34% (titration)
33% in absolute ethanol (~5.6 M)

density

0.76 g/cm3

functional group

amine

SMILES string

CNC

InChI

1S/C2H7N/c1-3-2/h3H,1-2H3

InChI key

ROSDSFDQCJNGOL-UHFFFAOYSA-N

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General description

Dimethylamine (DMA) is a versatile organic compound that is commonly used in organic synthesis as a reagent and building block for various reactions. It is also used as a base in several reactions such as the Mannich reaction and Michael addition.

Application

Dimethylamine solution (33% in absolute ethanol) can be used in a sialic acid ethyl esterification reaction. It is also used as a reagent in the Pd-catalyzed C-N bond-forming cross-coupling reactions.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

3.2 °F - closed cup

Flash Point(C)

-16 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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C Mulder et al.
Journal of neural transmission (Vienna, Austria : 1996), 109(9), 1203-1208 (2002-08-31)
Nitric oxide (NO) may play a role in the pathophysiology of Alzheimer's disease (AD). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, is involved in regulation of NO production. Recently it has been reported that dimethylarginine dimethylaminohydrolase, an enzyme
L Lee et al.
Cancer research, 41(10), 3992-3994 (1981-10-01)
Using a method for nitrosamine analysis that gives high recovery values and that is free from artifactual synthesis of nitrosamines, we have shown that human feces do not contain volatile nitrosamines (detection limit, 0.1 to 0.5 microgram/kg). We also showed
Gerhild Zauner et al.
Biochimica et biophysica acta, 1820(9), 1420-1428 (2011-08-02)
Analysis of protein glycosylation is an important first step towards establishing the functions of glycans in health and disease. In contrast to N-glycans which are generally enzymatically released for analysis, there is no corresponding enzyme for O-glycan liberation. Therefore, O-glycans
George Nicholson et al.
PLoS genetics, 7(9), e1002270-e1002270 (2011-09-21)
We have performed a metabolite quantitative trait locus (mQTL) study of the (1)H nuclear magnetic resonance spectroscopy ((1)H NMR) metabolome in humans, building on recent targeted knowledge of genetic drivers of metabolic regulation. Urine and plasma samples were collected from
Meric Selbes et al.
Water research, 47(2), 945-953 (2012-12-15)
N-nitrosodimethylamine (NDMA), a probable human carcinogen, is a disinfection by-product that has been detected in chloraminated and chlorinated drinking waters and wastewaters. Formation mechanisms and precursors of NDMA are still not well understood. The main objectives of this study were

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