286656
α-Methyl-DL-phenylalanine
98%
Synonym(s):
(±)-2-Amino-2-methyl-3-phenylpropionic acid
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About This Item
Linear Formula:
C6H5CH2C(CH3)(NH2)CO2H
CAS Number:
Molecular Weight:
179.22
Beilstein:
2803960
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
reaction suitability
reaction type: solution phase peptide synthesis
mp
293-294 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
CC(N)(Cc1ccccc1)C(O)=O
InChI
1S/C10H13NO2/c1-10(11,9(12)13)7-8-5-3-2-4-6-8/h2-6H,7,11H2,1H3,(H,12,13)
InChI key
HYOWVAAEQCNGLE-UHFFFAOYSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Effect of phenylalanine, p-chlorophenylalanine and alpha-methylphenylalanine on glucose uptake in vitro by the brain of young rats.
N R Rodrigues et al.
Biochemical Society transactions, 18(3), 419-419 (1990-06-01)
M S de Freitas et al.
Neurochemistry international, 26(4), 381-385 (1995-04-01)
We studied the effects of L-phenylalanine and alpha-methylphenylalanine on 32P in vitro incorporation into cytoskeletal proteins from cerebral cortex of 17-day-old rats. Slices of cerebral cortex were incubated in the absence or presence of increasing concentrations of L-phenylalanine, alpha-methylphenylalanine or
A Diamond et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 14(5 Pt 2), 3072-3082 (1994-05-01)
Phenylketonuria (PKU) is a genetic disorder in which the hydroxylation of phenylalanine (Phe) to tyrosine is severely disrupted. If PKU is left untreated, severe mental retardation results. The accepted treatment is to restrict dietary intake of Phe. It has generally
S Ma et al.
Journal of chromatography. A, 1216(18), 3784-3793 (2009-03-13)
Enantiomeric separation of two aromatic alpha-substituted alanine esters was achieved on two commercially available polysaccharide-based chiral stationary phases (CSPs): amylose tris(3,5-dimethylphenylcarbamate) (ADMPC) and cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC). The interactions between enantiomeric analytes and the CSPs were investigated using chromatographic methods and
B J Strupp et al.
Developmental psychobiology, 17(2), 109-120 (1984-03-01)
Experimental phenylketonuria was induced in male rats by daily injections of alpha-methylphenylalanine and phenylalanine on postnatal Days 3-31. Beginning at 8 weeks of age, the animals were subjected to a test of observational learning followed by a test of latent
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