Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

133361

Sigma-Aldrich

2-Naphthalenesulfonyl chloride

99%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H7ClO2S
CAS Number:
93-11-8
Molecular Weight:
226.68
Beilstein:
641898
EC Number:
202-219-9
MDL number:
MFCD00004087
UNSPSC Code:
12352100
PubChem Substance ID:
24848104
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

200

Assay

99%

form

solid

bp

147.7 °C/0.6 mmHg (lit.)

mp

74-76 °C (lit.)

SMILES string

ClS(=O)(=O)c1ccc2ccccc2c1

InChI

1S/C10H7ClO2S/c11-14(12,13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H

InChI key

OPECTNGATDYLSS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2-Naphthalenesulfonyl chloride was employed as capping reagent for primary amine to convert histamine to a selective histamine H3-receptor antagonist[1]. It was used for pre-column derivatization during the high-performance liquid chromatographic assay of neomycin sulfate[2].

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCC4085
BCBZ4853
BCBS7190V
BCBT7847
BCBS2631V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

M J Tozer et al.
Bioorganic & medicinal chemistry letters, 9(13), 1825-1830 (1999-07-16)
Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data from the various bioassays were achieved with the 2-naphthalensulfonamides of histamine homologues.
K Tsuji et al.
Journal of chromatography, 333(2), 365-380 (1985-10-04)
A normal-phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of spectinomycin hydrochloride and spectinomycin sulfate for detection at 254 nm. The method involves pre-column derivatization of secondary amines of spectinomycin with 2-naphthalenesulfonyl chloride (NSCl) using a
K Tsuji et al.
Journal of chromatography, 369(1), 105-115 (1986-11-07)
A normal phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of neomycin sulfate. The method involves pre-column derivatization with 2-naphthalenesulfonyl chloride (NSCl) followed by extraction in chloroform and chromatography using a normal phase silica column with

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service