Skip to Content
Merck
All Photos(3)

Documents

S0327

Sigma-Aldrich

Scutellarein

≥98% (HPLC)

Synonym(s):

4′,5,6,7-Tetrahydroxyflavone, 6-Hydroxyapigenin

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
529-53-3
Molecular Weight:
286.24
MDL number:
MFCD00017692
UNSPSC Code:
12352200
PubChem Substance ID:
329824421
NACRES:
NA.25

biological source

Erigeron breviscapus

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

yellow

solubility

DMSO: 1 mg/mL, clear, greenish-yellow

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

Oc1ccc(cc1)C2=CC(=O)c3c(O)c(O)c(O)cc3O2

InChI

1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H

InChI key

JVXZRQGOGOXCEC-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Flavonoid that is selectively cytotoxic toward cancer cells. Induces mitochondrial ROS, DNA damage, and metabolic suppression, preferentially in tumor cells. Scutellarein has been shown to have better absorption than scutellarin in Caco-2 monolayer cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xuesong Liu et al.
Journal of pharmaceutical sciences, 100(6), 2452-2459 (2011-01-20)
Antisolvent crystallization can be used as an alternative to cooling or evaporation for the separation and purification of solid product in the pharmaceutical industry. To improve the process understanding of antisolvent crystallization, the use of in-line tools is vital. In
Y H Tao et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 15(1-2), 92-97 (2007-08-11)
Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter, is metabolized by the successive action of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH). Inhibition of both enzymes in brain tissues increases the GABA level and may have therapeutic applications in neurological
Vivian Chen et al.
PloS one, 7(1), e30107-e30107 (2012-01-25)
Bezielle is a botanical extract that has selective anti-tumor activity, and has shown a promising efficacy in the early phases of clinical testing. Bezielle inhibits mitochondrial respiration and induces reactive oxygen species (ROS) in mitochondria of tumor cells but not
Jian-feng Xing et al.
Acta pharmacologica Sinica, 32(5), 655-663 (2011-04-26)
To study the metabolic and pharmacokinetic profile of scutellarin, an active component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz, and to investigate the mechanisms underlying the low bioavailability of scutellarin though oral or intravenous administration in rats. HPLC method
Wenmiao Li et al.
Antiviral research, 177, 104714-104714 (2020-03-14)
Myricetin, a common dietary flavonoid, was reported to possess many different biological activities such as anti-oxidant, anti-inflammatory, and antiviral effects. In this study, we explored the anti-HSV effects and mechanisms of myricetin both in vitro and in vivo. The results
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service