RAB0160
Human EGFR / ErbB1 ELISA Kit
for serum, plasma, cell culture supernatants and urine
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... EGFR(1965)
General description
Epidermal growth factor receptor (EGFR) is a member of the epidermal growth factor receptor tyrosine kinase (RTK) family. It is a single-chain transmembrane glycoprotein. EGFR comprises an extracellular ligand-binding ectodomain, a short juxtamembrane section, a transmembrane domain, a tyrosine kinase domain, tyrosine-containing C-terminal tail. Overexpression of EGFR is observed in breast cancer cells.
Immunogen
Recombinant Human EGFR
Application
Human EGFR / ErbB1 ELISA Kit has been used in the estimation of epidermal growth factor receptors (EGFR) from human epithelial cells. It has also been used in the detection of EGFR from patient plasma/serum and exosomes isolated from human prostate cancer cells LNCaP xenografts.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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Yi Zhao et al.
Cancer research, 80(11), 2217-2229 (2020-03-21)
Stemness and epithelial-mesenchymal transition (EMT) are two fundamental characteristics of metastasis that are controlled by diverse regulatory factors, including transcription factors. Compared with other subtypes of breast cancer, basal-type or triple-negative breast cancer (TNBC) has high frequencies of tumor relapse.
Takumi Fujiwara et al.
Cancers, 12(10) (2020-10-25)
Background: Lung cancer is the leading cause of mortality for cancer worldwide. A point mutation in exon 21 of the epidermal growth factor receptor resulting in the substitution of arginine for leucine at position 858 (L858R) is a frequent cause
Lingmei Huang et al.
Scientific reports, 7(1), 11084-11084 (2017-09-13)
Biomass fuel smoke is thought to contribute to chronic obstructive pulmonary disease, which is characterized by mucous cell metaplasia and enhanced mucus secretion. We investigated the effect of particulate matter (PM) with a diameter <2.5 μm (PM2.5) from wood smoke
Jiao-Jiao Yu et al.
Nature communications, 11(1), 3660-3660 (2020-07-23)
High expression or aberrant activation of epidermal growth factor receptor (EGFR) is related to tumor progression and therapy resistance across cancer types, including non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitors (TKIs) are first-line therapy for NSCLC. However, patients
Martin Siegemund et al.
Scientific reports, 8(1), 7808-7808 (2018-05-19)
Single-chain formats of TNF-related apoptosis inducing ligand (scTRAIL) can serve as effector components of tumour-associated antigen-targeted as well as non-targeted fusion proteins, being characterized by high tumour cell-specific induction of apoptosis through death receptor activation. We studied the suitability of
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