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32904

Supelco

Cefalonium hydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H18N4O5S2 · xH2O
CAS Number:
5575-21-3
Molecular Weight:
458.51 (anhydrous basis)
EC Number:
226-948-7
MDL number:
MFCD11975221
UNSPSC Code:
41116107
PubChem Substance ID:
329754381
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

O.NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4cccs4)C3=O)C([O-])=O)cc1

InChI

1S/C20H18N4O5S2.H2O/c21-17(26)11-3-5-23(6-4-11)9-12-10-31-19-15(18(27)24(19)16(12)20(28)29)22-14(25)8-13-2-1-7-30-13;/h1-7,15,19H,8-10H2,(H3-,21,22,25,26,28,29);1H2/t15-,19-;/m1./s1

InChI key

GVIOXNHDFXYYMP-AEFICSSHSA-N

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General description

Cefalonium is a cephalosporin antibiotic which belongs to the β-lactam class, used in both human and veterinary medicine. Its mode of action involves inhibiting of enzymes involved in the biosynthesis of cell wall peptidoglycan resulting in the lysis of bacteria.
Chemical structure: ß-lactam

Application

Cefalonium hydrate may be used for the determination of cefalonium in bovine muscle by liquid chromatography coupled to tandem mass spectrometry.
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9388
BCCF4758
BCCF0213
BCBV1595
SZBD126XV

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R W Shephard et al.
Australian veterinary journal, 82(10), 624-629 (2005-05-13)
To investigate and compare the therapeutic efficacy of dry cow agents containing either cephalonium or cloxacillin within Australian dairy herds. A treatment-control trial. Milk from infected quarters of cows with high somatic cell counts in milk on eight Australian dairy
J E Hillerton et al.
Journal of dairy science, 82(4), 704-711 (1999-04-23)
The use of antibiotic therapy to treat and prevent udder infections of cows during the dry period is a key component of mastitis control in many countries. At the same time, the general public is becoming increasingly aware of potential
G Ziv et al.
The Veterinary quarterly, 3(2), 74-79 (1981-04-15)
The comparative efficacy of a product containing 500 mg benzathine cloxacillin (Orbenin D.C.). another product containing 100 mg nafcillin, 300 mg procaine benzylpenicillin and 100 mg dihydrostreptomycin (Nafpenzal D.C.) and a third product containing 250 mg cephalonium (Cepravin D.C.), in
M A Bryan et al.
New Zealand veterinary journal, 59(4), 166-173 (2011-06-11)
To test equivalence between two different cephalonium dry-cow therapy (DCT) products with regard to the incidence of bacteriological cure of existing infections of quarters, the incidence of new intramammary infections (IMI) from 2-5 days postpartum and the incidence of clinical
S McDougall
New Zealand veterinary journal, 58(1), 45-58 (2010-03-05)
To test the non-inferiority of a novel cephalonium formulation of antibiotic dry-cow therapy (DCT) to a reference formulation, infused at the end of lactation, for cure of existing and prevention of new intramammary infections (IMI). Cows with a maximum somatic
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