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M9768

Sigma-Aldrich

Cysteamine

~95%

Synonym(s):

β-Mercaptoethylamine, 2-Aminoethanethiol, 2-Mercaptoethylamine, Decarboxycysteine, MEA, Thioethanolamine

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About This Item

Linear Formula:
NH2CH2CH2SH
CAS Number:
60-23-1
Molecular Weight:
77.15
Beilstein:
635649
EC Number:
200-463-0
MDL number:
MFCD00008196
UNSPSC Code:
12352100
PubChem Substance ID:
57654428
NACRES:
NA.22

Assay

~95%

form

solid

storage temp.

2-8°C

SMILES string

NCCS

InChI

1S/C2H7NS/c3-1-2-4/h4H,1-3H2

InChI key

UFULAYFCSOUIOV-UHFFFAOYSA-N

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Application

Cysteamine is an amino thiol drug mainly used in the treatment of cystinosis. It is an antioxidant with chemo-sensitizing and radioprotective properties.

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Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer.
Fujisawa T, et al.
PLoS ONE, 7(4), e34437-e34437 (2012)
Ravendra Naidoo et al.
Bacteriophage, 2(1), 15-24 (2012-06-06)
Bacteriophages offer interesting alternatives to antibodies for the specific capture and detection of pathogenic bacteria onto biosensing surfaces. Procedures for the optimal chemical immobilization of lytic bacteriophages onto surfaces are presented. More specifically, the removal of lysate contaminants from bacteriophage
Dandan Fang et al.
Mikrochimica acta, 186(9), 608-608 (2019-08-09)
An ultrasensitive competitive-type electrochemiluminescence immunoassay for the mycotoxin zearalenone is described. The method is based on the use of (a) a mimotope peptide that was selected from a phage displayed peptide library and used to substitute ZEN for designing the
L Vécsei et al.
Progress in neuro-psychopharmacology & biological psychiatry, 14(6), 835-862 (1990-01-01)
1. Cysteamine is formed by degradation of coenzyme A (CoA) and causes somatostatin (SS), prolactin and noradrenaline depletion in the brain and peripheral tissues. 2. Cysteamine influences several behavioral processes, like active and passive avoidance behavior, open-field activity, kindled seizures
A de Graaf-Hess et al.
Clinical chemistry, 45(12), 2224-2228 (1999-12-10)
Cystinosis is a rare inborn error of cystine transport, leading to accumulation of cystine in the lysosomes. To diagnose cystinosis and monitor treatment with cysteamine, adequate measurements of cystine concentrations in leukocytes and cultured fibroblasts are required. Cells were sonicated
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