V105

S(−)-Verapamil hydrochloride hydrate

≥98% (HPLC), powder

• Empirical Formula (Hill Notation): C₂₇H₃₈N₂O₄ · HCl · xH₂O
• CAS Number: 36622-28-3
• Molecular Weight: 491.06 (anhydrous basis)
• NACRES: NA.77
• PubChem Substance ID: 24900705
• UNSPSC Code: 12352200
• EC Number: 253-132-8
• MDL number: MFCD11045898
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]22/D −6.1°, c = 0.1 in ethanol(lit.)
• storage condition: desiccated, protect from light
• color: white to beige
• solubility: H₂O: >30 mg/mL, ethanol: soluble
• SMILES string: O.Cl.COc1ccc(CCN(C)CCC[C@](C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
• InChI: 1S/C27H38N2O4.ClH.H2O/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H;1H2/t27-;;/m0../s1
• InChI key: ICKXRKHJKXMFLR-LPCSYZHESA-N

Description

Biochem/physiol Actions

Active enantiomer of (±)-verapamil. Ca²⁺ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.

Features and Benefits

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Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges