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Merck

SML3277

HDL mimetic peptide 4F trifluoroacetate

≥95% (HPLC)

Synonym(s):

Ac-DWFKAFYDKVAEKFKEAF-NH2 trifluoroacetate, L-4F trifluoroacetate, N-Acetyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-lysyl-L-alanyl-L-phenylalanyl-L-tyrosyl-L-α-aspartyl-L-lysyl-L-valyl-L-alanyl-L-α-glutamyl-L-lysyl-L-phenylalanyl-L-lysyl-L-α-glutamyl-L-alanyl-L-phenylalaninamide trifluoroacetate

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About This Item

NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
powder
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Quality Segment

assay

≥95% (HPLC)

form

powder

color

white to beige

storage temp.

−20°C

Biochem/physiol Actions

Brain blood barrier penetrant small amphipathic peptide that exhibits anti-inflammatory, antioxidant and anti-atherogenic properties in animal models.
HDL mimetic peptide 4F is a brain blood barrier penetrant small amphipathic peptide that exhibits anti-inflammatory, antioxidant and anti-atherogenic properties in animal models. HDL mimetic peptide 4F increases the brain efflux of intracerebrally injected 125I-Aβ42. It suppresses proinflammatory monocytes and macrophages and alleviates post myocardial infarction remodeling in a mouse model.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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