M9766

4-Methylumbelliferyl α-D-glucopyranoside

α-glucosidase substrate, fluorogenic, ≥99% (TLC), powder

• Synonym(s): 4-Methylumbelliferyl α-D-glucoside
• Empirical Formula (Hill Notation): C₁₆H₁₈O₈
• CAS Number: 17833-43-1
• Molecular Weight: 338.31
• NACRES: NA.32
• PubChem Substance ID: 24897365
• UNSPSC Code: 12352204
• EC Number: 241-794-0
• MDL number: MFCD00067661
• Beilstein/REAXYS Number: 1690776

Properties

• Product Name: 4-Methylumbelliferyl α-D-glucopyranoside, α-glucosidase substrate
• Quality Segment: 300
• assay: ≥99% (TLC)
• form: powder
• solubility: pyridine: 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12
• InChI: 1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/m1/s1
• InChI key: YUDPTGPSBJVHCN-JZYAIQKZSA-N

Description

Application

4-Methylumbelliferyl ǥ-D-glucopyranoside has been used to assay acid alpha-glucosidase (GAA) activity in tissue homogenates.[1][1][2]

Biochem/physiol Actions

4-Methylumbelliferyl ǥ-D-glucopyranoside serves as a fluorogenic substrate for the ǥ-glucosidase enzyme. The product, 4-methylumbelliferyl, shows a peak at 440nm in the fluorescence spectra.[3]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)