If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
M6045
2-Methyl-4-isothiazolin-3-one hydrochloride
≥99%
Synonym(s):
MIT hydrochloride, Methylisothiazolinone hydrochloride
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About This Item
Quality Segment
biological source
synthetic
assay
≥99%
form
powder
concentration
≤ 100%
technique(s)
cell culture | mammalian: suitable
color
white to beige
mp
165—170 °C ((329 - 338 °F) at ca.990.4 hPa)
solubility
water: soluble 10.0 — 10.4 mg/mL, clear, colorless to faint yellow or tan
suitability
suitable for component for culture media
application(s)
microbiology
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
Cl[H].CN1SC=CC1=O
InChI
1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
InChI key
SJXPQSRCFCPWQQ-UHFFFAOYSA-N
General description
Application
- as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death[1]
- to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| mode of action protein synthesis | interferes | mode of action - | mode of action protein synthesis | interferes | mode of action - |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) - | technique(s) - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| assay ≥99% | assay ≥94.0% (GC), 95% | assay - | assay - |
| suitability suitable for component for culture media | suitability - | suitability - | suitability - |
| application(s) microbiology | application(s) - | application(s) - | application(s) agriculture |
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1
supp_hazards
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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