G0903

γ-Glu-Cys

≥80% (HPLC), suitable for ligand binding assays

• Synonym(s): γ-L-Glutamyl-L-cysteine, des-Gly-glutathione reduced form
• Empirical Formula (Hill Notation): C₈H₁₄N₂O₅S
• CAS Number: 636-58-8
• Molecular Weight: 250.27
• MDL number: MFCD00237863
• UNSPSC Code: 12352209
• PubChem Substance ID: 24895030
• NACRES: NA.26

Properties

• product name: γ-Glu-Cys, ≥80% (HPLC)
• Assay: ≥80% (HPLC)
• form: powder
• composition: Peptide content, ≥60% elemental analysis
• technique(s): ligand binding assay: suitable
• color: white to off-white
• storage temp.: −20°C
• SMILES string: N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O
• InChI: 1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1
• InChI key: RITKHVBHSGLULN-WHFBIAKZSA-N

Description

Amino Acid Sequence

Glu-Cys

Application

γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues.

Biochem/physiol Actions

γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides.

Physical form

Lyophilized from 0.1% TFA.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves