C0780

Creatine

suitable for cell culture

• Synonym(s): (α-Methylguanido)acetic acid, N-Amidinosarcosine
• Linear Formula: H₂NC(=NH)N(CH₃)CH₂CO₂H
• CAS Number: 57-00-1
• Molecular Weight: 131.13
• NACRES: NA.26
• PubChem Substance ID: 24892273
• UNSPSC Code: 12352209
• EC Number: 200-306-6
• MDL number: MFCD00004282
• Beilstein/REAXYS Number: 907175

Properties

• Product Name: Creatine, anhydrous
• grade: anhydrous
• Quality Segment: 200
• form: powder
• technique(s): cell culture | mammalian: suitable
• color: white
• SMILES string: CN(CC(O)=O)C(N)=N
• InChI: 1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)
• InChI key: CVSVTCORWBXHQV-UHFFFAOYSA-N

Description

Application

Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.

Biochem/physiol Actions

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP.

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves