The stability of this compound in solution, specifically in DMSO, has not been evaluated. However, external sources note that Budesonide is stable in DMSO for up to 1 year at -20°C or up to 2 years at -80°C. Store in working aliquots, avoid repeated freeze/thaw cycles.
B7777
Budesonide
≥99%, anti-inflammatory, powder
Synonym(s):
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
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About This Item
Empirical Formula (Hill Notation):
C25H34O6
CAS Number:
Molecular Weight:
430.53
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
257-139-7
MDL number:
Assay:
≥99%
Form:
powder
Pricing and availability is not currently available.
Product Name
Budesonide, ≥99%
Quality Segment
assay
≥99%
form
powder
originator
AstraZeneca
SMILES string
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(CCC)O[C@@]45C(=O)CO
InChI
1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
InChI key
VOVIALXJUBGFJZ-KWVAZRHASA-N
Gene Information
human ... IFNG(3458), IL5(3567), NR3C1(2908)
rat ... Nr3c1(24413)
Biochem/physiol Actions
Second generation glucocorticoid with low systemic absorption; anti-inflammatory agent; inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein.
Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.
Features and Benefits
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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This Item | |||
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| form powder | form - | form - | form - |
| assay ≥99% | assay ≥97% | assay - | assay - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| originator AstraZeneca | originator Roche | originator - | originator - |
| Gene Information human ... IFNG(3458), IL5(3567), NR3C1(2908) | Gene Information - | Gene Information human ... NR3C1(2908) | Gene Information - |
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - Skin Sens. 1 - STOT RE 1 Inhalation
target_organs
Adrenal gland
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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I resuspended 250mg in 581µl of DMSO (soluble). How should I store this and for how long can I keep it. Thank you in advance :)
1 answer-
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