B3503
Benzidine
≥98%
Synonym(s):
4,4′-Diaminobiphenyl
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About This Item
Empirical Formula (Hill Notation):
C12H12N2
CAS Number:
Molecular Weight:
184.24
UNSPSC Code:
12352116
NACRES:
NA.25
PubChem Substance ID:
EC Number:
202-199-1
Beilstein/REAXYS Number:
742770
MDL number:
Assay:
≥98%
Quality level:
Quality Level
assay
≥98%
SMILES string
Nc1ccc(cc1)-c2ccc(N)cc2
InChI
1S/C12H12N2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8H,13-14H2
InChI key
HFACYLZERDEVSX-UHFFFAOYSA-N
Gene Information
human ... UGT1A4(54657)
Application
Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.
Biochem/physiol Actions
Initiates tumors in the bladder under experimental conditions.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Benzidine: a bladder carcinogen.
R G Wendel et al.
The Journal of urology, 111(5), 607-610 (1974-05-01)
Yaoyun Duan et al.
Cell death & disease, 10(10), 766-766 (2019-10-12)
The yolk sac is the first site of blood-cell production during embryonic development in both murine and human. Heat shock proteins (HSPs), including HSP70 and HSP27, have been shown to play regulatory roles during erythropoiesis. However, it remains unknown whether
Brian J Pak et al.
PLoS neglected tropical diseases, 8(8), e3002-e3002 (2014-08-08)
Strongyloidiasis is a persistent human parasitic infection caused by the intestinal nematode, Strongyloides stercoralis. The parasite has a world-wide distribution, particularly in tropical and subtropical regions with poor sanitary conditions. Since individuals with strongyloidiasis are typically asymptomatic, the infection can
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B3503-5G | 04061833428115 |
| B3503-10G | 04061833428092 |
| B3503-1G | 04061833428108 |