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Merck

44213

Thromboplastin from rabbit

Synonym(s):

Thromboplastin, Factor III, Thrombokinase

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About This Item

CAS Number:
UNSPSC Code:
12352202
EC Number:
276-433-6
NACRES:
NA.25
MDL number:
Form:
lyophilized solid
Biological source:
rabbit
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biological source

rabbit

form

lyophilized solid

UniProt accession no.

storage temp.

2-8°C

Gene Information

rabbit ... F3(100009127)

Application

Thromboplastin from rabbit has been used:
  • as a standard in tissue factor procoagulant activity assay (TF-PCA)
  • in pulmonary embolism assay
  • as a positive control in clotting assay using human plasma

Biochem/physiol Actions

Thromboplastin (Tissue factor) is a transmembrane protein, the chief in vivo activator of blood coagulation that leads to thrombin generation and fibrin deposition. It is also important in the activation of the coagulation protease cascade and is involved in the lethality of sepsis.,
Thromboplastin from rabbit might be used to produce disseminated intravascular coagulation (DIC) in animal models.

Packaging

One vial contains 3-4 mg thromboplastin.

Preparation Note

Reconstitute the content of 1 vial in 4 ml 10 mm CaCl2


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)



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