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137272

Guanidine hydrochloride

EMPROVE® EVOLVE

Synonym(s):

Guanidine hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

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About This Item

Linear Formula:
NH2C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
95.53
UNSPSC Code:
12352107
Beilstein/REAXYS Number:
3591990
MDL number:
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biological source

synthetic

Quality Segment

product line

EMPROVE® EVOLVE

form

powder

impurities

Endotoxin, microbial, and trace metals; tested

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)

solubility

water: 6 M at 20 °C, clear, colorless

density

1.3 g/cm3 (lit.)

suitability

suitable for manufacturing use

application(s)

downstream processes
pharma/biopharma processes

storage temp.

2-30°C

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

General description

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
G32725095050933
description

EMPROVE® EVOLVE

description

Molecular Biology, ≥99%

description

≥98%

description

BioUltra, Molecular Biology, ≥99.5% (AT)

form

powder

form

crystalline powder

form

powder or crystals

form

powder or crystals

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

product line

EMPROVE® EVOLVE

product line

-

product line

-

product line

BioUltra

solubility

water: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M, clear, colorless

solubility

H2O: 6 M, clear (100 Hazen)

solubility

H2O: 6 M at 20 °C, clear, colorless

biological source

synthetic

biological source

synthetic (organic)

biological source

-

biological source

synthetic

suitability

suitable for manufacturing use

suitability

-

suitability

-

suitability

-


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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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