SMB00981
2-Hydroxymelatonin
≥95% (HPLC)
Synonym(s):
2-OH MEL, 2-OHM, 2-OHMET, 2OHM, N-[2-(2,3-Dihydro-5-methoxy-2-oxo-1H-indol-3-yl)ethyl]acetamide, N-[2-(2-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide, AMIO
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About This Item
Empirical Formula (Hill Notation):
C13H16N2O3
CAS Number:
Molecular Weight:
248.28
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.21
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General description
Melatonin (MT) is metabolized into several derivatives, including N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N1-acetyl-5-methoxykynuramine (AMK), 6-hydroxymelatonin, 2-hydroxymelatonin, 3-hydroxymelatonin, and cyclic 3-hydroxymelatonin. MT and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants.
Application
Metabolomics research
Other Notes
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Sung Ho Lee et al.
Biochemical and biophysical research communications, 527(4), 941-946 (2020-05-23)
2-Hydroxymelatonin is a metabolite produced when melatonin 2-hydroxylase catalyzes melatonin. Recent studies have reported the important roles of melatonin in bone metabolism. However, the roles of 2-hydroxymelatonin in bone metabolism remains poorly understood. The purpose of this study is to
Anis Ali Shah et al.
Chemosphere, 243, 125308-125308 (2019-11-14)
Cadmium level is continuously increasing in agricultural soils mainly due to anthropogenic activities. Cadmium is one of the most phytotoxic metals in the soils. The present study investigates the possible role of 2-hydroxymelatonin (2-OHMT) in assuagement of Cd-toxicity in cucumber
Ewy A Mathé et al.
Cancer research, 74(12), 3259-3270 (2014-04-17)
Lung cancer remains the most common cause of cancer deaths worldwide, yet there is currently a lack of diagnostic noninvasive biomarkers that could guide treatment decisions. Small molecules (<1,500 Da) were measured in urine collected from 469 patients with lung
Kyoungwhan Back
The Plant journal : for cell and molecular biology, 105(2), 376-391 (2020-07-10)
Melatonin is a multifunctional biomolecule found in both animals and plants. In this review, the biosynthesis, levels, signaling, and possible roles of melatonin and its metabolites in plants is summarized. Tryptamine 5-hydroxylase (T5H), which catalyzes the conversion of tryptamine into
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