![trans-4-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide Dye content 98 %](/deepweb/assets/sigmaaldrich/product/structures/416/722/5d59b6c3-5f2d-4396-a721-5cb82ba7038c/640/5d59b6c3-5f2d-4396-a721-5cb82ba7038c.png)
This product is not tested for solubility. For absorbance testing, it is dissolved in methanol. Reference papers describe preparing stock solutions at 1mg/ml in methanol. There are 10 mM solutions available from other suppliers that are prepared in DMSO.
390062
Thiazole Orange
Dye content ~90 %
Synonym(s):
1-Methyl-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]quinolinium p-tosylate
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C26H24N2O3S2
CAS Number:
Molecular Weight:
476.61
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
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form
powder
Quality Level
composition
Dye content, ~90%
technique(s)
titration: suitable
mp
270 °C (dec.) (lit.)
λmax
512 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Cc1ccc(cc1)S([O-])(=O)=O.CN2C(\Sc3ccccc23)=C\c4cc[n+](C)c5ccccc45
InChI
1S/C19H17N2S.C7H8O3S/c1-20-12-11-14(15-7-3-4-8-16(15)20)13-19-21(2)17-9-5-6-10-18(17)22-19;1-6-2-4-7(5-3-6)11(8,9)10/h3-13H,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
InChI key
ACOJCCLIDPZYJC-UHFFFAOYSA-M
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General description
Thiazole Orange can be tethered with peptide nucleic acid for the detection of target nucleic acid in homogeneous solution.[1] It is a dye with, both predicted physical characteristics and the biological staining characteristics of a good reticulocyte dye, hence it is considered as a dye for reticulocyte analysis. It has massive fluorescence enhancement and high quantum yield upon binding to nucleic acids, particularly RNA. It is non precipitating and can permeates through live cell membranes.[2]
Application
Thiazole orange has been used for the staining and thereby quantification of reticulocytes.[3]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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