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18493

Millipore

MUG Supplement

suitable for microbiology

Synonym(s):

4-Methylumbelliferyl-β-D-glucuronide, 4-Methylumbelliferyl-β-D-glucuronide Supplement, MUGlcU

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About This Item

Empirical Formula (Hill Notation):
C16H16O9
CAS Number:
6160-80-1
Molecular Weight:
352.29
EC Number:
228-186-0
MDL number:
MFCD00036772
UNSPSC Code:
41171614
PubChem Substance ID:
329751679
NACRES:
NA.85

sterility

sterile

Quality Level

100

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Escherichia coli
coliforms

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C(O)=O)O[C@H]1OC2=CC(OC(C=C3C)=O)=C3C=C2

InChI

1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key

ARQXEQLMMNGFDU-JHZZJYKESA-N

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Application

Fluorogenic substrate for measuring of ß-glucoronidiase activity, for identifiacation of Escherichia coli.

Components

(per vial, sufficient for 500 ml medium)
4-Methylumbelliferyl ß-D-glucuronide (MUG) 50.0 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH4341
BCCG4785
BCCD8551
BCCC7285
BCCC1629

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Adrian Unc et al.
Applied and environmental microbiology, 72(3), 2287-2289 (2006-03-07)
Laboratory batch tests indicate that addition of sterile municipal sewage biosolids to clay soil from four depths increases the numbers of Escherichia coli isolates recoverable in EC-MUG broth (EC broth with 4-methylumbelliferyl-beta-glucuronide). This effect was most marked for the deeper
M Grube et al.
Naunyn-Schmiedeberg's archives of pharmacology, 368(6), 463-469 (2003-11-18)
A promising development in tumor therapy is the application of non-toxic prodrugs from which the active cytostatic is released by endogenous enzymes such as beta-glucuronidase (beta-gluc). Regulation of beta-gluc expression is one crucial factor modulating bioactivation of prodrugs. Recent experiments
Si-Cheng Liang et al.
Journal of pharmaceutical and biomedical analysis, 54(1), 236-241 (2010-09-11)
Propofol O-glucuronidation has been used as probe reaction to phenotype UGT1A9 activity in human liver, thus a sensitive and specific method for determination of propofol O-glucuronide (PG) is urgently desirable. In the current study, a new LC-ESI-MS method for determination
Mizuki Ninomiya et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(2), 225-232 (2004-10-28)
We investigated whether the species difference in the biliary excretion activity of some Mrp2 substrates was attributable to the intrinsic transport potential or the expression level of Mrp2, especially in rat and dog. Dog Mrp2 cDNA was isolated from beagle
Bernhard Sperker et al.
Life sciences, 71(13), 1547-1557 (2002-07-20)
Antibody directed enzyme prodrug therapy (ADEPT) using glucuronide prodrugs is an experimental approach to reduce systemic toxicity of anti-cancer agents. Bioactivation of such prodrugs is achieved by fusion proteins consisting of targeting moieties (e.g. ligands of tumor specific antigens) and
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