04704

Glycidamide

analytical standard

• Synonym(s): 2,3-Epoxypropanamide, Oxiranecarboxamide
• Empirical Formula (Hill Notation): C₃H₅NO₂
• CAS Number: 5694-00-8
• Molecular Weight: 87.08
• Beilstein: 227 163 2
• EC Number: 227-163-2
• MDL number: MFCD00468053
• UNSPSC Code: 41116107
• PubChem Substance ID: 329747975
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥95% (qNMR)
• shelf life: limited shelf life, expiry date on the label
• application(s): environmental
• format: neat
• storage temp.: 2-8°C
• SMILES string: NC(=O)C1CO1
• InChI: 1S/C3H5NO2/c4-3(5)2-1-6-2/h2H,1H2,(H2,4,5)
• InChI key: FMAZQSYXRGRESX-UHFFFAOYSA-N

Description

General description

Glycidamide, an active epoxide metabolite of acrylamide with potential biological activity, can be generated in vivo. Its mutagenic and genotoxic nature is well-known.

Application

Glycidamide may be used as an analytical standard for the determination of the analyte in human and animal biological samples by various chromatography techniques.

Other Notes

In the summer of 2008 research scientists at the Technical University of Munich besides acrylamide detected glycidamide in potato crisps. Glycidamide is a metabolite of acrylamide.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H317,H319,H335,H350
• Precautionary Statements: P201 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves