810130P
Avanti
16:0-06:0 NBD PC
Avanti Research™ - A Croda Brand 810130P, powder
Synonym(s):
1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C36H62N5O11P
CAS Number:
Molecular Weight:
771.88
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810130P-1mg)
pkg of 5 × 1 mg (810130P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810130P
shipped in
dry ice
storage temp.
−20°C
General description
16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) is a fluorescent analogue of phosphatidylcholine.
Application
16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) has been used in NBD-phospholipid translocation assay. It may be used as a molecular fluorescent marker to label lipids during the friction tests, as substrate for enzyme substrate specificity determination and in the preparation of small unilamellar vesicles.
Biochem/physiol Actions
16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) acts as a potential fluorescent probe. It is used for the quantification of the soluble and membrane-bound phospholipase A2 (PLA2) activity. 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) derivatives are widely used as fluorescent analogs of native lipids in biological and model membranes to study a variety of processes.
Packaging
5 mL Amber Glass Screw Cap Vial (810130P-1mg)
5 mL Amber Glass Screw Cap Vial (810130P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
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In vitro analysis of the Staphylococcus aureus lipoteichoic acid synthase enzyme using fluorescently labeled lipids
Karatsa-Dodgson MW, et al.
Journal of Bacteriology, 192(20), 5341-5349 (2010)
Effects of fluorescent probe NBD-PC on the structure, dynamics and phase transition of DPPC. A molecular dynamics and differential scanning calorimetry study
Loura L, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(2), 491-501 (2008)
The use of C6-NBD-PC for assaying phospholipase A2-activity: scope and limitations
Meyuhas D, et al.
Biochimica et Biophysica Acta, Lipids and Lipid Metabolism, 1124(3), 223-232 (1992)
Role of the biomolecular interactions in the structure and tribological properties of synovial fluid
Mirea DA, et al.
Tribology International, 59(3), 302-311 (2013)
Kevin N Baumann et al.
ACS nano, 14(2), 2316-2323 (2020-01-25)
The self-assembly of the protein clathrin on biological membranes facilitates essential processes of endocytosis and has provided a source of inspiration for materials design by the highly ordered structural appearance. By mimicking the architecture of the protein building blocks and
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