V113

S(+)-γ-Vigabatrin

solid

• Synonym(s): S(+)-γ-Vinyl GABA, S(+)-4-Aminohexenoic acid
• Empirical Formula (Hill Notation): C₆H₁₁NO₂
• CAS Number: 74046-07-4
• Molecular Weight: 129.16
• NACRES: NA.77
• PubChem Substance ID: 24900710
• UNSPSC Code: 12352200
• MDL number: MFCD00274076
• Form: solid

Properties

• form: solid
• Quality Segment: 100
• optical activity: [α]/D +11.8°, c = 2.5 in H₂O(lit.)
• color: off-white
• solubility: H₂O: >20 mg/mL, ethanol: soluble
• storage temp.: 2-8°C
• SMILES string: N[C@@H](CCC(O)=O)C=C
• InChI: 1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m1/s1
• InChI key: PJDFLNIOAUIZSL-RXMQYKEDSA-N

Description

Application

S(+)-γ-Vigabatrin has been used as a standard in ultra-high-performance-liquid-chromatography (UHPLC).

Biochem/physiol Actions

GABA transaminase inhibitor; anti-convulsant.

γ-Vigabatrin has the potential to treat infantile spasms and seizures. It exhibits therapeutic effects against cocaine and other addictions.

Disclaimer

Hygroscopic

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H372
• pcodes: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves