D3132

Silver diethyldithiocarbamate

• Synonym(s): DETC, Diethyldithiocarbamic acid silver salt
• Linear Formula: (C₂H₅)₂NCSSAg
• CAS Number: 1470-61-7
• Molecular Weight: 256.14
• Beilstein: 3718150
• EC Number: 216-003-7
• MDL number: MFCD00004929
• UNSPSC Code: 12171500
• PubChem Substance ID: 57654088
• NACRES: NA.47

Properties

• form: powder
• mp: 172-175 °C (lit.)
• solubility: pyridine: 25 mg/mL, clear, yellow
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 2-8°C
• SMILES string: CCN(CC)C(=S)S[Ag]
• InChI: 1S/C5H11NS2.Ag/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1
• InChI key: NSVHDIYWJVLAGH-UHFFFAOYSA-M

Description

Application

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Also used for colorimetric determination of small quantities of arsenic.
Silver diethyldithiocarbamate has been used in cell culture.

Also used for colorimetric determination of small quantities of arsenic

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.
Silver diethyldithiocarbamate (AgDDC) is used to estimate the level of arsenic in human.

Inhibits induction of macrophage nitric oxide synthase.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves