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256A-1

Sigma-Aldrich

Gastrin Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (256A-14)
vial of 0.5 mL concentrate (256A-15)
bottle of 1.0 mL predilute (256A-17)
vial of 1.0 mL concentrate (256A-16)
bottle of 7.0 mL predilute (256A-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

stomach

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... GAST(2520)

Related Categories

General description

Gastrin is a polypeptide hormone produced by G-cells in the gastric antrum and duodenal mucosa that serves as an important regulator of gastric acid secretion. Gastrin is useful for the identification of gastrin-secreting non-neoplastic and neoplastic neuroendocrine cells. Anti-Gastrin antibody gives positive staining of G-cells of human antral/pyloric mucosa and cells producing gastrin or a structural gastrin analogue as is seen in the stomach; no staining of other cells or tissue types has been observed. This antibody may react with sulfated and non-sulfated forms of gastrin. The antibody cross-reacts with more than 50% of the present choleocystokinin octapeptide.

Quality


IVD
IVD
IVD
RUO

Linkage

Gastrin (polyclonal) Positive Control Slides, Product No. 256S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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L Bornstein-Quevedo et al.
Human pathology, 32(11), 1252-1256 (2001-12-01)
Carcinoid tumors of the ampulla of Vater (ACs) differ from duodenal carcinoid tumors (DCs). A search for AC and DC was made between 1980 and 2000. The clinicopathologic features and follow-up were assessed. Immunohistochemistry for panneuroendocrine markers, hormone products, proliferating
J F Rehfeld et al.
The Journal of biological chemistry, 256(20), 10426-10429 (1981-10-25)
The anterior, intermediate, and neural lobes of porcine pituitaries contain different molecular forms of gastrin. In the anterior lobe, unsulfated large gastrins, component I, and gastrin-34 constitute the main forms. In contrast in the intermediate and neural lobes, gastrin-17, sulfated
Expression of gastrin and its receptor in human gastric cancer tissues.
Hur, Keun et al
Journal of Cancer Research and Clinical Oncology, 132,2, 85-91 (2006)
Gastrin and Gastric Cancer.
Smith, Jill P et al.
Cellular and molecular gastroenterology and hepatology, 75-83, 75-83 (2017)
Immunohistochemical identification and localisation of gastrin and somatostatin in endocrine cells of human pyloric gastric mucosa.
Kasacka, I et a
Folia Morphologica (Praha.), 71,1, 39-44 (2012)
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